| Name | Character | Episodes |
|---|---|---|
| Sherman Hemsley | Willie Goode | 23 |
| Scott Grimes | Garth | 23 |
| Gabrielle Union | Tracy Monaghan | 23 |
| Bianca Lawson | Bianca Goode | 23 |
| Joseph Maher | Chancellor Willoughby | 23 |
| Alex Datcher | Barbara Goode | 23 |
| Dorien Wilson | Franklin Goode | 23 |
| Justina Machado | Raquel DeLaRosa | 4 |
| Bryan Cranston | Record Executive | 1 |
| Wendie Malick | Dr. Stephanie Krienberg | 1 |
| Beth Grant | Pearl | 1 |
| Don Lake | 1 | |
| Graham Jarvis | Marty | 1 |
| Van Epperson | Bubba | 1 |
| George Wyner | Mr. Kent | 1 |
| Michael Dempsey | Dad | 1 |
| Dan Martin | Lloyd | 1 |
| Harrison Page | Dr. Fleming | 1 |
| Alex Rocco | 1 | |
| Diane Delano | Debbie Caruthers | 1 |
| Michael Ensign | 1 | |
| Christopher Darga | Bob | 1 |
| Kevin Crowley | Lyle Erskin | 1 |
| Fergie | Self | 1 |
| Janet Hubert | Dr. Pamela Fordham | 1 |
| Marc McClure | Harry Danielson | 1 |
| Macon McCalman | Mr. Kaufman | 1 |
| Jim Fyfe | Les Fenster | 1 |
| Mandy Ingber | 1 |