| Name | Character | Episodes |
|---|---|---|
| Michael Sheen | Michael | 20 |
| David Tennant | David | 20 |
| Georgia Tennant | Georgia | 20 |
| Nina Sosanya | Jo | 5 |
| Whoopi Goldberg | Mary | 3 |
| Ben Schwartz | Tom | 3 |
| Jim Broadbent | Jim | 2 |
| Adrian Lester | Adrian | 2 |
| Peter de Jersey | Peter | 2 |
| Cate Blanchett | Cate | 1 |
| Samuel L. Jackson | Sam | 1 |
| Christoph Waltz | Christoph | 1 |
| Ben Schwartz | Ben | 1 |
| Ewan McGregor | Ewan | 1 |
| Olivia Colman | Olivia | 1 |
| Nick Frost | Nick | 1 |
| Simon Pegg | Simon | 1 |
| Jim Parsons | Jim | 1 |
| Hugh Bonneville | Hugh | 1 |
| Judi Dench | Judi | 1 |
| Ken Jeong | Ken | 1 |
| Josh Gad | Josh | 1 |
| Phoebe Waller-Bridge | Phoebe | 1 |
| Michael Palin | Michael | 1 |
| Neil Gaiman | Neil Gaiman | 1 |
| Lenny Henry | Len | 1 |
| Romesh Ranganathan | Romesh | 1 |
| Lily Mo Sheen | Lily (uncredited) | 1 |
| Ty Tennant | Ty | 1 |