| Each episode of this part talk show, part docuseries begins with animal-loving celebrities showcasing their pets. The showcase transitions into a documentary segment on the species previously showcased, followed by a discussion with an animal expert, and concluding with host Betty White and sometimes her guest stars outside with a wild animal. |
| Name | Character | Episodes |
|---|---|---|
| Allen Ludden | Self - Announcer (voice | 39 |
| Betty White | Self - Host | 39 |
| Burt Reynolds | Self | 1 |
| Michael Landon | Self | 1 |
| Vincent Price | Self | 1 |
| Allen Ludden | Self | 1 |
| Eve Arden | Self | 1 |
| Eddie Albert | Self | 1 |
| Carol Burnett | Self | 1 |
| Barbara Bain | Self | 1 |
| Amanda Blake | Self | 1 |
| Barbara Eden | Self | 1 |
| James Stewart | Self | 1 |
| Dennis Weaver | Self | 1 |
| Shirley Jones | Self | 1 |
| Lorne Greene | Self | 1 |
| Eva Gabor | Self | 1 |
| Beverly Garland | Self | 1 |
| Agnes Moorehead | Self | 1 |
| Doris Day | Self | 1 |
| Barbara Feldon | Self | 1 |
| Nancy Kulp | Self | 1 |
| Mary Tyler Moore | Self | 1 |
| Rod Serling | Self | 1 |
| Merv Griffin | Self | 1 |
| Peter Lawford | Self | 1 |
| Bill Bixby | Self | 1 |
| Bob Crane | Self | 1 |
| Jim Nabors | Self | 1 |
| James Brolin | Self | 1 |
| Mike Connors | Self | 1 |
| Sue Ane Langdon | Self | 1 |
| Pat Carroll | Self | 1 |
| Richard Deacon | Self | 1 |
| Miyoshi Umeki | Self | 1 |
| Donald O'Connor | Self | 1 |
| Bob Barker | Self | 1 |
| Paul Lynde | Self | 1 |
| Della Reese | Self | 1 |
| Peter Marshall | Self | 1 |
| Arte Johnson | Self | 1 |
| Johnny Mathis | Self | 1 |