| Name | Character | Episodes |
|---|---|---|
| Dana Delany | Ellie Cain | 13 |
| Jeremy Sisto | Lucian Knapp | 13 |
| Carmen Ejogo | Turner | 13 |
| Timothy Hutton | Conrad Cain | 13 |
| Mykelti Williamson | Virgil Hayes | 13 |
| Delroy Lindo | Latimer King | 13 |
| Linus Roache | Andy Archer | 13 |
| Michael Mosley | Malcolm Atkins | 13 |
| Robert John Burke | Bellows | 13 |
| Will Denton | Leopold Cain | 13 |
| Otto Sanchez | 9 | |
| Doug Hutchison | 7 | |
| James Urbaniak | 6 | |
| Olivia Thirlby | 5 | |
| Jamie Tirelli | 5 | |
| Anthony Rapp | 4 | |
| Mädchen Amick | Vivian Guttman | 3 |
| Audra McDonald | 3 | |
| Amy Ryan | 2 | |
| Elizabeth Marvel | 2 | |
| Robert Foxworth | 2 | |
| Titus Welliver | 1 | |
| Giancarlo Esposito | 1 | |
| Desmond Harrington | 1 | |
| Ritchie Coster | 1 | |
| Ebon Moss-Bachrach | 1 | |
| Alison Bartlett | 1 | |
| Victoria Cartagena | 1 | |
| Adam LeFevre | 1 | |
| Terry Kinney | 1 | |
| Michelle Hurd | 1 | |
| Kerry O'Malley | 1 | |
| Tom Noonan | 1 | |
| Peter Gerety | 1 | |
| Brennan Brown | 1 | |
| Chance Kelly | 1 | |
| Maury Ginsberg | 1 | |
| Jace Alexander | 1 |