| Name | Character | Episodes |
|---|---|---|
| Hannes Jaenicke | Dr. Daniel Koch | 17 |
| Tilo Nest | Kriminalhauptkommissar Ralf Brandt | 17 |
| Charly Hübner | Dr. Thomas Renner | 17 |
| Waldemar Kobus | Prof. Brehme | 1 |
| Florian Panzner | Toni Hofner | 1 |
| Lisa Maria Potthoff | Gabriele Baum | 1 |
| Christian Redl | Pater Arrango | 1 |
| Florian Bartholomäi | Erik Dahlberg | 1 |
| Niels Bormann | Markus Hoffmann | 1 |
| Roland Schäfer | Prof. Klaus Darmstedt | 1 |
| Jürgen Rißmann | Detlev Meinholdt | 1 |
| Mimi Fiedler | Nina Krug | 1 |
| Joachim Paul Assböck | Oberstabsarzt Dr. Schneider | 1 |
| Tilo Prückner | Wolfgang Karlsen | 1 |
| Constantin von Jascheroff | Tom Glanzel | 1 |
| Horst Sachtleben | Max Heimlich | 1 |
| Arnd Klawitter | Albert Peeck | 1 |
| Sabine Postel | Charlotte Schoop | 1 |
| Nicole Marischka | Bea Engel | 1 |
| Daniela Preuss | Anette Steek | 1 |
| Iris Böhm | Barbara May | 1 |
| Hanno Friedrich | Kriminalkommissar Junghans | 1 |
| Hans-Uwe Bauer | Thorsten Möller | 1 |
| Steffen Münster | Martin Wiese | 1 |
| Esther Zimmering | Nadja | 1 |
| Andreas Patton | Engler | 1 |
| Christoph Ortmann | Andreas Wertheim | 1 |
| Kai Ivo Baulitz | Dr. Biel | 1 |
| Kerstin Linnartz | Monika Thomstedt | 1 |
| Johanna Gastdorf | Dorothea Möller | 1 |
| Hannes Wegener | Guido Baum | 1 |
| Tim Wilde | Phil Grothmann | 1 |
| Gitta Schweighöfer | Kathrin Schwenke | 1 |