| Name | Character | Episodes |
|---|---|---|
| Frank Welker | Garfield (voice) | 203 |
| Audrey Wasilewski | Arlene (voice) | 203 |
| Jason Marsden | Nermal (voice) | 203 |
| Gregg Berger | Odie / Squeak (voice) | 203 |
| Wally Wingert | Jon Arbuckle (voice) | 203 |
| Julie Payne | Dr. Liz Wilson (voice) | 203 |
| Laura Summer | Drusilla / Minerva the Twins (voice) | 145 |
| Laraine Newman | Aunt Ivy (voice) | 2 |
| June Foray | Mrs. Cauldron (voice) | 2 |
| Laraine Newman | Winona (voice) | 1 |
| Laraine Newman | Chicken (voice) | 1 |
| Jason Marsden | Professor Bonkers (voice) | 1 |
| Jack Riley | Ghost Cat (voice) | 1 |
| Gregg Berger | Mr. Barker (voice) | 1 |
| Laura Summer | Drusilla / Minerva (voice) | 1 |