| Name | Character | Episodes |
|---|---|---|
| Melissa Villaseñor | Nellie Ramírez-Humphrey (voice) | 55 |
| Myrna Velasco | Tater Ramírez-Humphrey (voice) | 38 |
| Cheech Marin | Pop Ramirez (voice) | 38 |
| Cristina Valenzuela | Tere Ramirez / Toñita Ramirez (voice) | 38 |
| Angélica María | Buela Ramirez (voice) | 38 |
| Nomi Ruiz | Tabi Ramirez (voice) | 38 |
| Elizabeth Grullón | Lita (voice) | 38 |
| Michelle Ortiz | Bibi Ramírez-Humphrey (voice) | 38 |