| Name | Character | Episodes |
|---|---|---|
| Rob LaBelle | Crazy Eddie | 66 |
| Sebastian Spence | Cade Foster | 66 |
| Roger Cross | Joshua | 16 |
| Roger Cross | Cain | 4 |
| Roger Cross | Joshua Bridges | 4 |
| Dana Brooks | Colonel Grace | 4 |
| Roger Cross | Joshua Bridges / Cain | 3 |
| Stacy Grant | Hannah Foster | 3 |
| Katharine Isabelle | Denise | 1 |
| Katharine Isabelle | Elizabeth | 1 |
| Ian Tracey | Garvin | 1 |
| Christina Cox | Jody Nolan | 1 |
| Emmanuelle Vaugier | Esther | 1 |
| Steve Bacic | Paul | 1 |
| Jason Gray-Stanford | Willet | 1 |
| Adam Beach | Alex Sherman | 1 |
| A. J. Cook | Lindsay Tilden | 1 |
| Myron Natwick | Emmett Mayhew | 1 |
| Christian Bocher | Richie Black | 1 |
| Campbell Lane | Uncle Harry | 1 |
| William deVry | Karl | 1 |
| Steve Byers | Medical Assistant (as Stephen Byers) | 1 |
| Brock Johnson | Calvin | 1 |
| Sarah Deakins | Alicia | 1 |
| Suzy Joachim | Gua Agent | 1 |
| Teryl Rothery | Dr. Heather LeGuin | 1 |
| Nicole Oliver | Lawyer | 1 |
| Nicole Oliver | Charlene Fay | 1 |
| Glenn Morshower | Sheriff John Holden | 1 |
| Kendall Cross | Jenny | 1 |
| Kendall Cross | Erin Sullivan | 1 |
| Tyler Labine | Billy | 1 |
| Graham Greene | Lonetree | 1 |
| Sarah Chalke | Chloe Wells | 1 |
| A.C. Peterson | Detective Walter | 1 |
| Ty Olsson | Richard | 1 |
| Kevin McNulty | Ryan | 1 |
| Joel Palmer | Young Cade Foster | 1 |
| Paul McGillion | Raphael | 1 |
| Christopher Judge | Xevallah | 1 |
| Tara Spencer-Nairn | Cassandra | 1 |
| Christopher Shyer | Lon | 1 |
| Ben Cotton | Gua Police | 1 |
| Brandy Ledford | Michelle | 1 |
| Camille Sullivan | Diana Black | 1 |
| Tom Butler | Sheriff Robey | 1 |
| Tom Butler | Bill Blaylock | 1 |
| Lauren K. Robek | Stacy | 1 |
| Colin Lawrence | Terrence | 1 |
| April Telek | Gibson | 1 |
| Stefanie von Pfetten | Waitress | 1 |
| Stefanie von Pfetten | Samantha Ray | 1 |
| Aaron Pearl | Det. Mike Olanski | 1 |
| Adrian Holmes | Jim | 1 |
| Adrian Holmes | Beckham | 1 |
| Blu Mankuma | Special Agent Haley Burbitt | 1 |
| Hiro Kanagawa | John Tran | 1 |
| Karen Holness | Rachel Cates | 1 |
| Sarah Strange | Henrietta / Hank | 1 |
| Sarah Lind | Dawn | 1 |
| Garwin Sanford | Trevor Hyams | 1 |
| Garwin Sanford | Nathan Brown | 1 |
| Mackenzie Gray | The Minister | 1 |
| Iris Quinn | Joanne Patterson | 1 |
| Nancy Sorel | Susan | 1 |
| Samantha Ferris | Alice | 1 |
| Peter Wingfield | Dr. Rook | 1 |
| Venus Terzo | Gua Supervisor | 1 |
| George Buza | Zachary | 1 |
| Kurt Max Runte | Finn | 1 |
| Allison Hossack | Gwen | 1 |
| Lisa Marie Caruk | Sondra | 1 |
| Kavan Smith | Tommy Cranston | 1 |
| Tim Henry | Officer Nash | 1 |
| Tim Henry | FBI Agent | 1 |
| Susan Hogan | Megan Loomis | 1 |
| Stephen E. Miller | Sheriff Haddock | 1 |
| Stephen E. Miller | Sgt Chernovsky | 1 |
| Elizabeth Thai | Clerk | 1 |
| Ian Robison | Everett Paul | 1 |
| Ian Robison | Hal | 1 |
| John Kapelos | Phil Tennant | 1 |
| William S. Taylor | DA Warren Phips | 1 |
| Rochelle Greenwood | Margaret | 1 |
| Michael Ryan | Senator Sterling Preston | 1 |
| Mark Gibbon | Guard | 1 |
| Mark Gibbon | Koch | 1 |
| Scott Heindl | Second Lieutenant Jordan Vincent | 1 |
| Ken Tremblett | Sheriff Randy Smithers | 1 |
| Ellen Dubin | Sarah Washburne | 1 |
| Eric Breker | Robert Foster | 1 |
| Michael Hogan | Mr. Bennett | 1 |
| Ellie Harvie | Marianne | 1 |
| Brad Kelly | Guard | 1 |
| Peter Bryant | Moody | 1 |
| William B. Davis | Sagon | 1 |
| David Fredericks | Frankie DeSalvo | 1 |
| Keegan Connor Tracy | Nicole | 1 |
| Helene Joy | Dr. Victoria Kelly | 1 |
| Adam J. Harrington | Acolyte | 1 |
| Brennan Elliott | Danny | 1 |
| Garry Chalk | Sheldon Lamott | 1 |
| Michelle Harrison | Melissa | 1 |
| Barbara Tyson | Dr. Mira Ruben | 1 |
| Natassia Malthe | Maid | 1 |
| Brenda Crichlow | Alice Moody | 1 |
| Victoria Pratt | Claire Wilson | 1 |
| Rena Marlette Lesnar | Lucas | 1 |
| Enuka Okuma | Alikah | 1 |
| Tanja Reichert | Nikki | 1 |
| Andrew Airlie | Dr.Reid | 1 |
| Andrew Airlie | Dr. Bern Galloway | 1 |
| Paul Johansson | Hatcher | 1 |
| Garvin Cross | Francis Jeffries | 1 |
| Kate Luyben | Mimi | 1 |
| Aaron Craven | Cop | 1 |
| Peter Kent | Sergeant Plimpton | 1 |
| Jim Byrnes | Tyler Greer | 1 |
| Trevor Devall | Tim Furlong | 1 |
| Patrick Keating | Coroner | 1 |
| David Millbern | George | 1 |
| Birkett Turton | Robbie Harlock | 1 |
| Fred Henderson | Ron Patterson | 1 |
| Ray Galletti | Defiant Man | 1 |
| Robert Wisden | James Dutton | 1 |
| Julie Patzwald | Vanessa | 1 |
| Duncan Fraser | Gen. Kendricks | 1 |
| Gordon Currie | Elton Beleye | 1 |
| David Paetkau | Elias | 1 |
| Peter Hanlon | Elroy Dunn | 1 |
| Gabrielle Miller | Molly Simon | 1 |
| Douglas O'Keeffe | Tanetti | 1 |
| Michael Puttonen | Sgt. Charlie Cobb | 1 |
| Anne Openshaw | Lady Lumina | 1 |
| Ken Kirzinger | Cop | 1 |
| Byron Lawson | Acolyte | 1 |
| Ingrid Torrance | Mary | 1 |
| Gillian Barber | Dr. Rita Hagen | 1 |
| Tobias Mehler | Jason | 1 |
| Andrew Jackson | Davis | 1 |
| Sam Vincent | Stanley Spencer | 1 |
| Malcolm Stewart | Dr. Pierce Malcolm | 1 |
| Bernard Cuffling | Frederick Lansing | 1 |
| David Christensen | Detective Saunders | 1 |
| Glen Gould | Dealer | 1 |
| Merrilyn Gann | Dr. Crane | 1 |
| Patricia Drake | Ellen | 1 |
| Patricia Drake | Cade's Mother | 1 |
| Anthony Harrison | Coach Glen Jenkins | 1 |
| Dean Marshall | Cop | 1 |
| Charles Zuckermann | Lanning | 1 |
| Tom McBeath | Dr. Zahn | 1 |
| John Novak | Det. Freddie Ludlow | 1 |
| Leanne Adachi | Acolyte | 1 |
| Ron Selmour | Colonel Nathan Pace | 1 |
| Chris Kramer | Acolyte | 1 |
| Zachary Ansley | Fergus McKay | 1 |
| John Tench | Jim | 1 |
| Rachel Hayward | Susan Tannen | 1 |
| Scott Bellis | Jinks Davis | 1 |
| Carolyne Maraghi | Caroline | 1 |
| Rod Wilson | Mabus / Dr. Oldham | 1 |
| Tyron Leitso | David | 1 |
| Tyron Leitso | Peter | 1 |
| Robert Moloney | Drew | 1 |
| Tiffany Lyndall-Knight | Gua Technician | 1 |
| Jennifer Copping | Kat Keith | 1 |
| Doug Abrahams | Officer Cronin | 1 |
| Jill Teed | Talia | 1 |
| Miranda Frigon | Tina | 1 |
| Lorena Gale | Alice Gundry | 1 |
| John B. Lowe | Priest | 1 |
| Wendel Meldrum | Ann Berman | 1 |
| Winston Rekert | Horace Burke | 1 |
| Claudette Mink | Shasha | 1 |
| Claudette Mink | Allegra | 1 |
| Kim Hawthorne | Agent Simon | 1 |
| Jay Brazeau | Speidel | 1 |
| Brent Stait | Dan McGuire | 1 |
| Vincent Gale | Peter Mincer | 1 |
| Andee Frizzell | Acolyte | 1 |
| Monika Schnarre | Harlie Daniels | 1 |
| Jonathan Walker | Jeff Draper | 1 |
| Kirby Morrow | Quentin Billup | 1 |
| Ernie Jackson | Apostle | 1 |
| David Lovgren | Elliot | 1 |
| James Kidnie | Max Sterman | 1 |
| Kirsten Zien | Emily | 1 |
| Desiree Zurowski | Sophia | 1 |
| Peter Flemming | Grant | 1 |
| Peter Flemming | Quinn | 1 |
| Tim Progosh | Dean Hormeth | 1 |
| Mark Humphrey | Trent | 1 |
| Will Sanderson | Ross Braxton | 1 |
| Will Sanderson | Clement | 1 |
| Rob Lee | Bert Samuel | 1 |
| Rob Lee | Gua Agent | 1 |
| Anthony Ulc | Hank | 1 |
| Johnny Cuthbert | Heckler | 1 |
| Michael St. John Smith | Gua Technician | 1 |
| Kevan Ohtsji | Technician | 1 |
| David Bloom | Francis Jeffries | 1 |
| Terry Barclay | Factory Manager | 1 |
| Terry Barclay | Doctor / Raven Nation Soldier (uncredited) | 1 |
| Terry Barclay | Doctor | 1 |
| Ben Bass | Russ | 1 |
| Heather Hanson | Lara | 1 |
| Janine Cox | Alana MacAfee | 1 |
| Margot Finley | Julia Hartman | 1 |
| Alex Zahara | Gregory | 1 |
| Lalainia Lindbjerg | Francesca Dutton | 1 |
| Mitchell Kosterman | State Trooper | 1 |
| Khaira Ledeyo | Nurse Cho | 1 |
| Rob Freeman | Doctor Ken | 1 |
| Suzanne Ristic | Coroner | 1 |
| J. Douglas Stewart | Deputy Brad Crowley | 1 |
| J. Douglas Stewart | Detective Neely | 1 |
| J. Douglas Stewart | Terry Smythe | 1 |
| Sandra P. Grant | Katherine Hutchinson | 1 |
| Jeff Seymour | Psychiatrist | 1 |
| Byron Lucas | Samuels | 1 |
| Brian Jensen | Adjunct General Stephen | 1 |
| David Palffy | Head of Security | 1 |
| Daniella Evangelista | Laura Bennett | 1 |
| Darryl Quon | Morgue Attendant | 1 |
| Stevie Vallance | Nurse Kelly | 1 |
| Woody Jeffreys | First Lieutenant Trevor Payne | 1 |
| Russell Ferrier | Colonel John Russell | 1 |
| Mark Holden | Officer | 1 |
| Kathryn Anderson | Pauline Lamott | 1 |
| Claude Knowlton | Cole | 1 |
| Paul Eckstein | Omar Healy | 1 |
| Jody Racicot | Chemist | 1 |
| John Tierney | Burgess | 1 |
| Connor Widdows | Patrick | 1 |
| Rebecca Reichert | Amsa | 1 |
| Stephen Park | Lorenzo | 1 |
| David Allan Pearson | Sam | 1 |
| Gerald Paetz | Apostle | 1 |
| Doris Chillcott | Patricia | 1 |
| Donny Lucas | Franklin Garver | 1 |
| Lisa Bunting | Francis Jeffries | 1 |
| Harrison Coe | Guard | 1 |
| Joely Collins | Anita | 1 |
| John MacDonald | Male Husk | 1 |
| Brent Fidler | Harold Shanley | 1 |
| Brent Fidler | Empiricist | 1 |
| Neil Denis | Skater | 1 |
| Laurie Paton | Mrs. Hitchens | 1 |
| Marcia Laskowski | Dr. Eldridge | 1 |
| Patrick McManus | JJ Reed | 1 |
| Amber Rothwell | Abbey | 1 |
| Marc Baur | Detective | 1 |
| Patricia Dahlquist | Martha Levi | 1 |
| Andrew Moxham | Acolyte | 1 |
| Richard Sargent | Alien | 1 |
| Darcy Belsher | Henry | 1 |
| Andrew Johnston | Sheriff | 1 |
| Elizabeth Carol Savenkoff | Yvonne | 1 |
| Richard Stroh | Gua Prison Guard | 1 |
| Alfonso Quijada | Raoul | 1 |
| Derek Morrison | Cop | 1 |
| Bob Frazer | Nate Barlowe | 1 |
| Charles Payne | Orderly | 1 |
| Bill Croft | Agent Dixon | 1 |
| Jennifer Jasey | Second Lieutenant Amy Lopez | 1 |
| Jennifer Jasey | Dr.Giddings | 1 |
| Eric Pospisil | Cody | 1 |
| Jano Frandsen | Jack Mitchum | 1 |
| Boyan Vukelic | Vincent | 1 |
| L. Harvey Gold | Judge R. Maxwell | 1 |
| L. Harvey Gold | Gua Judge | 1 |
| Peter Yunker | Headmaster | 1 |
| Greg Thirloway | Herman Garrett | 1 |
| Michelle Hart | Friend | 1 |
| Howard Dell | Gua Detective | 1 |
| J. B. Bivens | Orderly Coogan | 1 |
| Sylvesta Stuart | Security Guard | 1 |
| Dario Delacio | Guard | 1 |
| Simon Webb | Professor Engel | 1 |
| Ian Carter | Aide | 1 |
| Ona Grauer | Olivia | 1 |
| Ona Grauer | Taryn | 1 |
| Ingrid Kavelaars | Darcy | 1 |
| Lisa Howard | Renee Ashford | 1 |
| Phillip Mitchell | Gua Agent | 1 |
| Brenda James | Rae | 1 |
| Bill Switzer | Nick Patterson | 1 |
| Richard Newman | Dr. Allenson | 1 |
| Rick Ravanello | First Lieutenant Joel Langley | 1 |
| Rick Ravanello | Anton | 1 |
| Chris Humphreys | Bishop | 1 |
| Michasha Armstrong | Choker Husk | 1 |
| Michasha Armstrong | Bartender | 1 |
| Jim Shield | Agent Chris Mitchell | 1 |