| Name | Character | Episodes |
|---|---|---|
| Christopher Chittell | Eric Pollard | 6883 |
| Dominic Brunt | Paddy Kirk | 6830 |
| Mark Charnock | Marlon Dingle | 6830 |
| Tony Audenshaw | Bob Hope | 6828 |
| Lesley Dunlop | Brenda Walker | 6804 |
| Lucy Pargeter | Chas Dingle | 6410 |
| Meg Johnson | Pearl Ladderbanks | 6343 |
| Chris Bisson | Jai Sharma | 6260 |
| Freddie Jones | Sandy Thomas | 6197 |
| John Bowe | Lawrence White | 6168 |
| Zoë Henry | Rhona Goskirk | 6100 |
| Duncan Preston | Doug Potts | 6063 |
| Gaynor Faye | Megan Macey | 6046 |
| Bill Ward | James Barton | 5553 |
| Steve Halliwell | Zak Dingle | 5114 |
| Jane Cox | Lisa Dingle | 5106 |
| Patrick Mower | Rodney Blackstock | 5087 |
| Emma Atkins | Charity Dingle | 4991 |
| John Middleton | Ashley Thomas | 4870 |
| Jeff Hordley | Cain Dingle | 4526 |
| James Baxter | Jake Doland | 4302 |
| Nick Miles | Jimmy King | 4122 |
| Ryan Hawley | Robert Sugden | 4122 |
| Linda Thorson | Rosemary King | 3568 |
| Shirley Stelfox | Edna Birch | 3568 |
| Kim Thomson | 3568 | |
| Andrew Whipp | Callum Rennie | 3568 |
| Peter Martin | Len Reynolds | 3568 |
| Richard Thorp | Alan Turner | 3568 |
| David Crellin | Billy Hopwood | 3568 |
| Ciarán Griffiths | 3568 | |
| Pauline Quirke | 3548 | |
| Luke Tittensor | Daz Eden | 3466 |
| Sian Reeves | Sally Spode | 3466 |
| Jenna Coleman | Jasmine Thomas | 3446 |
| Patsy Kensit | Sadie King | 3446 |
| Kelvin Fletcher | Andy Sugden | 3446 |
| Sammy Winward | Katie Sugden | 3446 |
| Maxwell Caulfield | Mark Wylde | 3302 |
| Danny Miller | Aaron Dingle | 3212 |
| Billy Hartman | Terry Woods | 3136 |
| Charlie Hardwick | Val Pollard | 2670 |
| Tom Lister | Carl King | 2670 |
| Natalie J. Robb | Moira Dingle | 2367 |
| Bhasker Patel | Rishi Sharma | 2069 |
| Sian Reese-Williams | Genesis Walker | 1756 |
| Katherine Dow Blyton | Harriet Flinch | 1452 |
| Joseph Gilgun | Eli Dingle | 1441 |
| Lorraine Chase | 1434 | |
| James Thornton | John Barton | 1196 |
| Sheree Murphy | Tricia Dingle | 1084 |
| Kenneth Farrington | Tom King | 915 |
| Michael Praed | Frank Clayton | 558 |
| Andrew Scarborough | Graham Foster | 558 |
| Sally Dexter | Faith Dingle | 558 |
| Shaun Thomas | Gerry Roberts | 558 |
| William Ash | Caleb Miligan | 507 |
| Gemma Atkinson | Carly Hope | 322 |
| Gillian Kearney | Emma Barton | 322 |
| Denise Black | Joanie Dingle | 322 |
| Pasha Bocarie | Rakesh Kotecha | 322 |
| Natalie Anderson | 310 | |
| Dominic Power | 310 | |
| Beth Cordingly | Ruby Fox-Miligan | 249 |
| Duncan Preston | 68 | |
| Glynis Barber | 20 | |
| Tony Haygarth | 14 | |
| Nicola Stapleton | 14 | |
| Jo Kendall | Peggy Skilbeck | 2 |
| Frazer Hines | Joe Sugden | 1 |
| Laura Howard | PC Emerson | 1 |
| Wendy Craig | Maisie | 1 |
| Davina McCall | 1 | |
| Rebecca Grant | Dr. Stamford | 1 |
| John Weaver | Simon | 1 |
| John Weaver | PC Hayes | 1 |
| John Weaver | Police Officer | 1 |
| Samuel Edward-Cook | Jason | 1 |
| Gail Harrison | Marian Wilks | 1 |
| David Paisley | Paramedic | 1 |
| Martyn Luke | Upmarket Hotel Guest | 1 |
| Philip Battley | Paul | 1 |
| John Glyn-Jones | Harry Jameson | 1 |