| Name | Character | Episodes |
|---|---|---|
| Joe Devlin | Sam Catchem | 39 |
| Ralph Byrd | Dick Tracy | 39 |
| Lois Collier | Fluff | 4 |
| John Harmon | J. Blackstone Springem | 4 |
| Raymond Hatton | The Mole | 4 |
| Frank Hagney | Mountain | 3 |
| George Pembroke | 3 | |
| Don Brodie | 2 | |
| George Pembroke | Namgib | 2 |
| Dabbs Greer | Shaky | 1 |
| John Doucette | 1 | |
| George Eldredge | 1 | |
| Percy Helton | Jewel Smuggler | 1 |
| Percy Helton | 1 | |
| Don Brodie | Wheels | 1 |
| Don Brodie | Z. V. Wheels | 1 |
| Richard Reeves | Dixon | 1 |
| Richard Reeves | Buck | 1 |
| Richard Reeves | Memory Long | 1 |
| Richard Reeves | 1 | |
| Richard Reeves | Counterman | 1 |
| Lyle Talbot | 88 Keyes | 1 |
| George Pembroke | Jewel Smuggler | 1 |