| 3 lbs is a drama that aired on CBS from November 14 to 28, 2006, replacing the cancelled series Smith. The show itself was then canceled three weeks later due to poor ratings. The title refers to the fact that the average human brain weighs approximately three pounds. The show follows the medical careers of prominent brain surgeon Doctor Douglas Hanson and his protégé, Jonathan Seger. The show was promoted as, "The next great medical drama." The theme song is "Calling All Angels" by Train. Eight episodes were made, and the five episodes that did not originally air in the United States are available on Amazon Unbox. The program filmed in New York City at the request of Tucci, who didn't want to be away from home to make the series. When the pilot was originally filmed Dylan McDermott played Dr. Doug Hanson, and Reiko Aylesworth played Dr. Adrienne Holland. |
| Name | Character | Episodes |
|---|---|---|
| Stanley Tucci | Douglas Hanson | 8 |
| Indira Varma | Adrianne Holland | 8 |
| Zabryna Guevara | Melania Ortiz | 8 |
| Mark Feuerstein | Jonathan Seger | 8 |
| Armando Riesco | Tom Flores | 8 |
| Cyrus Farmer | Isaiah | 3 |
| Griffin Dunne | Dr. Jerry Cole | 2 |
| Jennifer Ferrin | Penny Marx | 2 |
| Ashlie Atkinson | Nurse Rhonda | 2 |
| Molly Bryant | Nurse Joanne | 2 |
| Madeline Zima | Cassie Mack | 1 |
| Cristin Milioti | Megan Rafferty | 1 |
| Cynthia Nixon | Dr. Karin Hanson | 1 |
| Julia Campbell | Roberta Mack | 1 |
| Maggie Siff | Lisa Ketchum | 1 |
| Addison Timlin | Charlotte Hanson | 1 |
| Jessica Hecht | Rebecca Ellis | 1 |
| Celia Weston | Tilly Bates | 1 |
| Nick Offerman | Dr. Coffey | 1 |
| Tamara Taylor | Della | 1 |
| Wrenn Schmidt | Female Student | 1 |
| Benjamin Walker | Nick Ross | 1 |
| Juliette Goglia | Erica Linden | 1 |
| Max Arciniega | Jose | 1 |
| Ned Eisenberg | Brad Ellis | 1 |
| Kate Jennings Grant | Kristen Lund | 1 |
| Jack Gilpin | Dr. Wardell | 1 |
| Gloria Garayua | Lucy Canet | 1 |
| Steve Braun | Otis Wills | 1 |
| Anna George | Helen Clark | 1 |
| Starla Benford | Ultrasound Nurse | 1 |
| Karl Bury | Matt Ketchum | 1 |
| Liz Burnette | Anesthesiologist | 1 |
| Sibyl Santiago | Nurse (uncredited) | 1 |