| Chyna Parks, an 11 year old musical prodigy, gets into a gifted program called Advanced Natural Talents at the local high school. Along with her fellow elementary school-aged 'ANTs', she must navigate the halls of a new school of older kids who are not particularly fond of grade-skipping newbies. |
| Name | Character | Episodes |
|---|---|---|
| China Anne McClain | Chyna Parks | 62 |
| Jake Short | Fletcher Quimby | 62 |
| Stefanie Scott | Lexi Reed | 62 |
| Sierra McCormick | Olive Doyle | 62 |
| Aedin Mincks | Angus Chestnut | 48 |
| Carlon Jeffery | Cameron Parks | 46 |
| Alexandria DeBerry | Paisley Houndstooth | 30 |
| Mindy Sterling | Susan Skidmore | 21 |
| Finesse Mitchell | Darryl Parks | 17 |
| Dominic Burgess | Zoltan Grundy | 15 |
| Zibby Allen | Winter Maddox | 7 |
| Matt Lowe | Hippo | 6 |
| Piper Curda | Kennedy Van Buren | 5 |
| Elise Neal | Roxanne Parks | 5 |
| Vanessa Morgan | Vanessa LaFontaine | 4 |
| Tom Choi | Mr. Hashimoto | 3 |
| Bonnie Morgan | Svetlana | 3 |
| Ben Winchell | Dixon Ticonderoga | 3 |
| Mark Teich | Mr. Zimbaldi | 3 |
| Ella Anderson | Hazel | 2 |
| Chris Rock | Himself | 1 |
| Zendaya | Sequoia Jones | 1 |
| Zibby Allen | Madam Goo Goo | 1 |
| Zibby Allen | Winter Maddox / Madam Goo Goo | 1 |
| Shelley Long | Mrs. Busby | 1 |
| James Hong | Kenny | 1 |
| Kyle S. More | Gnocchi | 1 |
| Jadon Sand | Gibson | 1 |
| Ernie Grunwald | Zanko | 1 |
| Hayley Erin | Duncan | 1 |
| Barry Williams | Game Show Host | 1 |
| Lauryn McClain | Lauryn | 1 |
| Vernee Watson-Johnson | Grammy | 1 |
| Kaylee Kaneshiro | Tina Garcetti | 1 |
| Austin North | Holland | 1 |
| Zayne Emory | Graham | 1 |
| Jessika Van | Sunshine | 1 |
| Michael Carbonaro | Nicky G | 1 |
| William Brent | Neville | 1 |
| Joey Luthman | Teen Zoltan | 1 |
| Nick Gracer | Demetri | 1 |
| Finesse Mitchell | Darryl Parks / Gus | 1 |
| Jeff Lewis | Bannister | 1 |
| Chris Wylde | Mr. Marceau | 1 |
| Sierra Aylina McClain | Sierra | 1 |
| Caroline Sunshine | Ella | 1 |
| Andrew Pifko | Bruce | 1 |
| Emily Robinson | Oksana | 1 |
| Connor Weil | Legan | 1 |
| Mews Small | Dakota | 1 |
| Jeremy Ford | James | 1 |
| Catero Colbert | Matari | 1 |
| Carrie Reichenbach | Justine | 1 |
| David H. Lawrence XVII | Leonard Battaro | 1 |