| 12-year-old Misaki Suzuhara has just gotten involved in Angelic Layer, a battling game using electronic dolls called angels. Even as a newbie, Misaki shows advanced skills as she meets new friends and enters Angelic Layer tournaments to fight the greatest Angelic Layer champions of the nation. |
| Name | Character | Episodes |
|---|---|---|
| Ayako Kawasumi | Kaede Saito (voice) | 26 |
| Satsuki Yukino | Tamayo Kisaki (voice) | 26 |
| Kotono Mitsuishi | Shoko Asami (voice) | 26 |
| Yui Horie | Hiromi Fujimori (voice) | 26 |
| Kikuko Inoue | Shuko Suzuhara (voice) | 26 |
| Tomokazu Seki | Masaharu Ogata (voice) | 26 |
| Ai Maeda | Kyoko's Follower B (voice) | 26 |
| Tomoko Kawakami | Madoka Fujisaki (voice) | 26 |
| Masaya Onosaka | Ichiro Mihara (voice) | 26 |
| Yuri Shiratori | Hatoko Kobayashi (voice) | 26 |
| Kappei Yamaguchi | 1 | |
| Tomoko Kaneda | 1 |