| Brother Cadfael is a twelfth-century Anglo-Welsh monk. A retired crusader disappointed in love, and now a herbalist in charge of the gardens of Shrewsbury Abbey, Brother Cadfael is often called on to solve murders and other crimes in and around Shrewsbury, Shropshire, in the border country where England meets Wales. |
| Name | Character | Episodes |
|---|---|---|
| Derek Jacobi | Brother Cadfael | 13 |
| Julian Firth | Brother Jerome | 13 |
| Michael Culver | Prior Robert | 13 |
| Albie Woodington | Sergeant Warden | 10 |
| Terrence Hardiman | Abbot Radulfus | 10 |
| Mark Charnock | Brother Oswin | 10 |
| Eoin McCarthy | Hugh Beringar | 6 |
| Sean Pertwee | Hugh Beringar | 4 |
| Peter Copley | Abbot Heribert | 4 |
| Anthony Green | Hugh Beringar | 3 |
| Sarah Badel | Avice of Thornbury | 2 |
| Toby Jones | Griffin | 1 |
| Natascha McElhone | Cecily Corde | 1 |
| Jonny Lee Miller | Edwin Gurney | 1 |
| Hugh Bonneville | Daniel Aurifaber | 1 |
| Lee Ingleby | Walter | 1 |
| Raad Rawi | Cassale | 1 |
| Jamie Glover | Simon | 1 |
| Sara Stephens | Rannilt | 1 |
| Ian McNeice | Canon Eluard | 1 |
| Jonathan Hyde | Godfrid Piccard | 1 |
| Julian Glover | Leoric Ashby | 1 |
| Tara Fitzgerald | Iveta de Massard | 1 |
| Danny Dyer | Bran | 1 |
| Rosalie Crutchley | Juliana Aurifaber | 1 |
| Stephen Moyer | Godwin | 1 |
| Crispin Bonham-Carter | Miles Coliar | 1 |
| Jonathan Firth | Joscelyn | 1 |
| Maggie O'Neill | Aline Siward | 1 |
| John Bennett | Lazarus the Leper | 1 |
| Hermione Norris | Mary | 1 |
| Natasha Little | Melangell | 1 |
| Tom Georgeson | Lord Giffard | 1 |
| Susan Fleetwood | Agnes Piccard | 1 |
| Norman Eshley | Baron Huon de Domville | 1 |
| Kitty Aldridge | Judith Perle | 1 |
| Robin Laing | Sulien | 1 |
| Robin Laing | Sulien Blount (uncredited) | 1 |
| Fiona Gillies | Susanna Aurifaber | 1 |
| Terence Beesley | Simeon Bagot | 1 |
| Anna Friel | Sioned | 1 |
| Ben Pullen | Ivo Corbiere | 1 |
| Peter Guinness | Father Ailnoth | 1 |
| Daniel Betts | Janyn | 1 |
| Richard Lintern | Lord Beaumont | 1 |
| John Hallam | Lord Rhysart | 1 |
| Amelia Curtis | Ermina Hugonin | 1 |
| Chloë Annett | Rosanna | 1 |
| Ronan Vibert | Le Gaucher | 1 |
| Robert Cavanah | Oliver de Bretagne | 1 |
| Christien Anholt | Meriet | 1 |
| Jack Klaff | Eudo | 1 |
| Tim Wylton | Geoffrey Corviser | 1 |
| Adrian Ross Magenty | Guy Fitzjohn | 1 |
| Jonathan Tafler | Money Lender | 1 |
| George Irving | Herluin | 1 |
| Barney Craig | Luc | 1 |
| Sebastian Abineri | Godfrey Fuller | 1 |
| Nigel Hastings | Giles Siward | 1 |
| John Bowler | Badon | 1 |
| Thomas Craig | Aelfric | 1 |
| Sean Chapman | William / Edmund | 1 |
| Tom Mannion | Niall Bronzesmith | 1 |
| Roger Ashton-Griffiths | Thomas of Bristol | 1 |
| Louise Delamere | Daalny | 1 |
| Michael Carman | Fitzalan | 1 |
| Ian Reddington | Peter Clemence | 1 |
| Marlene Sidaway | Flescher's Wife | 1 |
| Geoffrey Leesley | Sheriff Prestcote | 1 |
| Natasha Pyne | Lady Donata | 1 |
| Rupert Holliday-Evans | Roger Dodd | 1 |
| Roger Booth | Baldwin Peche | 1 |
| Aubrey Richards | Brother Rhys | 1 |
| Jeremy Young | Arnulf of Hesdin | 1 |
| Paul Trussell | Bertred | 1 |
| Niven Boyd | Sergeant | 1 |
| Michael Nightingale | Ailwin Corde | 1 |
| Paul Broughton | Baron's Steward | 1 |
| Michael Grandage | King Stephen | 1 |
| Gregor Truter | Ruald | 1 |
| Sophie Lawrence | Aldith | 1 |
| Adam Bareham | Cynric | 1 |
| Valentine Pelka | Richard Boterel | 1 |
| Christian Burgess | Adam Courcelle | 1 |
| Patrick Toomey | Tristan | 1 |
| Richard Clifford | Glover of Shotwick | 1 |
| Barna Illyés | Edward Perle | 1 |
| Jacqueline Defferary | Emma Vernold | 1 |
| Mary Miller | Richildis | 1 |
| Bernard Gallagher | Gervase Bonel | 1 |
| Graham McGrath | Brother Eluric | 1 |
| Hilary Sesta | Old Crone | 1 |
| Richard Henders | Torold Blund | 1 |
| Peter Baldwin | Prior Mortimer | 1 |
| Philip Herbert | Rabble Rouser | 1 |
| Phil Rowlands | Bened | 1 |
| Frank Baker | Remy | 1 |
| Steven Mackintosh | Liliwin | 1 |