| Name | Character | Episodes |
|---|---|---|
| Brenda Blethyn | DCI Vera Stanhope | 56 |
| Jon Morrison | DC Kenny Lockhart | 50 |
| Kenny Doughty | DS Aiden Healy | 35 |
| Ibinabo Jack | DC Jacqueline 'Jac' Williams | 23 |
| David Leon | DS Joe Ashworth | 16 |
| Paul Kaye | Dr Malcolm Donahue | 15 |
| Paul Ritter | Billy Cartwright | 12 |
| Sonya Cassidy | Celine Ashworth | 12 |
| Kingsley Ben-Adir | Dr Marcus Summer | 12 |
| Noof Ousellam | DC Hicham Cherradi | 8 |
| Cush Jumbo | DC Bethany Whelan | 7 |
| Wunmi Mosaku | DC Holly Lawson | 5 |
| Clare Calbraith | DC Rebecca Shepherd | 5 |
| Christopher Colquhoun | Dr. Anthony Carmichael | 4 |
| David Leon | DI Joe Ashworth | 3 |
| Steve Evets | PC George Wooten | 3 |
| Naomi Ackie | Louise Everitt | 1 |
| Rose Leslie | Lena Holgate | 1 |
| Cosmo Jarvis | Woody | 1 |
| Phyllis Logan | Shirley | 1 |
| Charlotte Hope | Saskia Barnes | 1 |
| Saskia Reeves | Sarah Marsden | 1 |
| Vincent Regan | Michael Glenn | 1 |
| Elizabeth Berrington | Paula | 1 |
| Juliet Aubrey | Felicity Calvert | 1 |
| Matilda Ziegler | Mary Culvert | 1 |
| Liam Cunningham | Sam Harper | 1 |
| Aisling Franciosi | Sigourney O'Brien | 1 |
| Gina McKee | Julie Armstrong | 1 |
| Jonathan Duttine | Lt. Colonel Chapell | 1 |
| Alexander Arnold | Sam Bishop | 1 |
| Marjorie Yates | Val Wilcox | 1 |
| Amerjit Deu | Bharat Mann | 1 |
| Charles De'Ath | Tony Hinshaw | 1 |
| Ian Bonar | Ewan Webster | 1 |
| Nasser Memarzia | Arjun Banerjee | 1 |
| Caroline Lee-Johnson | Darlene Houghton | 1 |
| Mark Addy | Tony Briggs | 1 |
| Clive Russell | Allen Barnes | 1 |
| Jill Halfpenny | Maggie Warnock | 1 |
| Jessica Barden | Stella Macken | 1 |
| Julie Graham | Marianne Gower | 1 |
| Charlie Heaton | Riley | 1 |
| Clare Higgins | Elaine Sidden | 1 |
| Rita Tushingham | Audrey Latham | 1 |
| Douglas Russell | Adam Gascoigne | 1 |
| Robert James-Collier | Richard | 1 |
| Danyal Ismail | Yousef Adwan | 1 |
| Sonita Henry | Sadie | 1 |
| Nina Sosanya | Chief Superintendent Rachel Waite | 1 |
| Daniel Ings | Simon | 1 |
| Clare Calbraith | DC Rebecca Shepard | 1 |
| Clare Calbraith | RMP Captain Shepard | 1 |
| David Calder | Frank McAffee | 1 |
| John Lynch | Edmund Fulwell | 1 |
| Mary Malone | Rae | 1 |
| Colin Tierney | Luke Shearwood | 1 |
| Gary Lewis | Robert Winter | 1 |
| Carolyn Pickles | Rita Fenton | 1 |
| Harriet Cains | Lizzie | 1 |
| Hugo Speer | Kieth Mantel | 1 |
| Shaun Dingwall | Justin Bishop | 1 |
| John Light | Andrew Franks | 1 |
| Kieran O'Brien | Bobby Salter | 1 |
| Ron Donachie | Jesse Hennings | 1 |
| Emily Joyce | Caroline Andersen | 1 |
| Francis Magee | Benny | 1 |
| Kerry Fox | Patricia Carmichael | 1 |
| Simon Harrison | Marcus Branagh | 1 |
| Alex Ferns | Michael Quinn | 1 |
| Peter Davison | Matthew Wells | 1 |
| Adam Long | Kyle | 1 |
| Sam Troughton | Noel | 1 |
| Lorraine Ashbourne | Barbara Tullman | 1 |
| Mark Bonnar | Danny Pryor | 1 |
| Paul Copley | Malcolm Kenrich | 1 |
| Ron Cook | Brian Gower | 1 |
| Jeany Spark | Agnes Lennox | 1 |
| Christopher Fairbank | Robert Naresby | 1 |
| Zoe Telford | Juliet Branagh | 1 |
| Lucy Russell | Susan Wakeland | 1 |
| Ann Mitchell | Moira Swann | 1 |
| Ronald Pickup | Mr. Kipford | 1 |
| Rita Davies | Soeur Benedict | 1 |
| Alistair Petrie | Stuart Bayliss | 1 |
| Faye Marsay | Christine | 1 |
| Richard Dillane | Will Peyton | 1 |
| Lee Ross | Frank O'Brien | 1 |
| Stuart Graham | Alan Marston | 1 |
| Angela Curran | Les enquêtes de Vera | 1 |
| Andrew Havill | Gareth Andersen | 1 |
| Garry Cooper | Cliff Cringle | 1 |
| Kevin Harvey | Clive Brock | 1 |
| Dean Andrews | Jonah Regan | 1 |
| Teresa Banham | Lorna Underwood | 1 |
| Craig Conway | Davy Sharp | 1 |
| Chanel Cresswell | Charlie | 1 |
| Lynn Farleigh | Valerie Furlow | 1 |
| Ian Burfield | Iain Hobswain | 1 |
| Frances Grey | Olivia Parmer | 1 |
| Stephen Walters | Nial Heslop | 1 |
| Simone Lahbib | Rose Swann | 1 |
| Ian Puleston-Davies | Sean Dewley | 1 |
| Robert Pugh | Eddie Thurston | 1 |
| David Wilmot | Mal Hinkin | 1 |
| Kevin Doyle | Ronnie Browne | 1 |
| Ben Batt | Tony Everitt | 1 |
| Kenneth Colley | Ronald Devreux | 1 |
| Penny Downie | Veronica | 1 |
| Ramanique Ahluwalia | Anita Sinha | 1 |
| Phoebe Thomas | Nicky | 1 |
| Alan Williams | Michael Long | 1 |
| Sean Campion | Guthrie | 1 |
| Eva Birthistle | Kate Darrow | 1 |
| Robert Glenister | Owen Preece | 1 |
| Kate Dickie | Nell Hinkin | 1 |
| Dorothy Atkinson | Shirley Hewarth | 1 |
| Patrick O'Kane | Terry Manttan | 1 |
| Raquel Cassidy | Gloria Edwards | 1 |
| David Lonsdale | Phil Annerly | 1 |
| Daniel Ryan | Alec Sidden | 1 |
| Craig Parkinson | Phil Swann | 1 |
| Esther Hall | Gayle | 1 |
| Caroline O'Neill | Kathy Bennions | 1 |
| Martin McCann | Jack Madden | 1 |
| Mark Benton | Stanley Booth | 1 |
| Sean Gilder | Bobby | 1 |
| Paul Higgins | Clive Stringer | 1 |
| Christine Kavanagh | Karen Kenworthy | 1 |
| Christine Bottomley | Lisa Strachan | 1 |
| William Ash | Linus Campion | 1 |
| Robert Wilfort | Cal Wallace | 1 |
| Steven Robertson | Tom Naresby | 1 |
| Melanie Kilburn | Susan Monkford | 1 |
| Ewan Stewart | Michael Hogarth | 1 |
| Jack Deam | Robert Falstone | 1 |
| Jamie Michie | Gary Webb | 1 |
| Velibor Topic | Milosh Beqiri | 1 |
| Patrick Baladi | Ross Varsey | 1 |
| Vinette Robinson | Corinne Franks | 1 |
| Hugh Quarshie | Dr. Leon Parmer | 1 |
| Nabil Elouahabi | Mo Hassan | 1 |
| Samantha Spiro | Belinda Rayford | 1 |
| Joe McGann | Julian Carr | 1 |
| Jonjo O'Neill | Gary Tovey | 1 |
| Aden Gillett | Harry Benton | 1 |
| Elizabeth Carling | Bev MacDonald | 1 |
| Bill Fellows | Alec | 1 |
| Paul Jesson | Dale Acreman | 1 |
| Matthew Marsh | Phil Kingston | 1 |
| Yusra Warsama | Zahra Suleiman | 1 |
| Paul Bown | Glynn Allen | 1 |
| Daniel Flynn | Godfrey Waugh | 1 |
| Jim Sturgeon | Robert Pryor | 1 |
| Martin Marquez | Michael Tennant | 1 |
| Billy Howle | Billy Shearwood | 1 |
| Dempsey Bovell | Jojo Walters | 1 |
| Mark Wingett | John Brace | 1 |
| Kerrie Hayes | Alice Wyatt | 1 |
| Niall Greig Fulton | Logan Tilley | 1 |
| Steven Hartley | Sgt Stuart Macken | 1 |
| Nicholas Gleaves | Tim Hopkins | 1 |
| Chelsea Edge | Kayleigh Mincham | 1 |
| Jo Hartley | Grace | 1 |
| Sophie Stanton | Andrea Hynde | 1 |
| Rebecca Benson | Ruthie Culvert | 1 |
| Mia McKenna-Bruce | Maya Draper | 1 |
| Daragh O'Malley | John Warrick | 1 |
| John Woodvine | Alan Kenworthy | 1 |
| Struan Rodger | Father O'Brien | 1 |
| Hebe Beardsall | Jennifer Marston | 1 |
| Philip Martin Brown | Stan Convile | 1 |
| Finn Atkins | Jodie | 1 |
| Cat Simmons | Lisa | 1 |
| James Nelson-Joyce | Jason McNeive | 1 |
| Souad Faress | Eve Jamshidi | 1 |
| Daniel Ezra | Cameron Thorne | 1 |
| Spike Leighton | Aaron Kirkstall | 1 |
| Nigel Betts | Brian Bennick | 1 |
| Louis Emerick | Jack Kassin | 1 |
| Ben Aldridge | Ben & Ollie Barton | 1 |
| Anna Wilson-Jones | Orla Cossdale | 1 |
| Jaye Griffiths | Marti Kapp | 1 |
| Steven Elder | Steve Devonshire | 1 |
| Jemima West | Laura Halcombe | 1 |
| Ben Crompton | Jason Glenn | 1 |
| Rosalind March | Harriet Stanhope | 1 |
| Tim Dutton | Aidan Carmichael | 1 |
| Lisa Kay | Clara Peyton | 1 |
| Ayesha Dharker | Anika Naidu | 1 |
| Lorcan Cranitch | Roy Brewer | 1 |
| Philip Arditti | John Greenhill | 1 |
| Ace Bhatti | Stuart Mayfield | 1 |
| Joe Dixon | George Haleford | 1 |
| Michael Hodgson | Thomas Kenworthy | 1 |
| Dave Hill | Larry Crowe | 1 |
| Alexander Cobb | David Walken | 1 |
| Rob Jarvis | Mick Mckittrick | 1 |
| Gary Mavers | Gerry Farr | 1 |
| Murray Head | Peter Calvert | 1 |
| Amaka Okafor | Laura Whitelock | 1 |
| Tim Woodward | Brian Delaney | 1 |
| Natalie Gumede | Megan Sibisi | 1 |
| Dorian Lough | Malcolm Raggert | 1 |
| Bill Ward | Peter Henson | 1 |
| Hannah Britland | Hannah | 1 |
| Mark Womack | Billy Reeves | 1 |
| Rakie Ayola | Amber Haleford | 1 |
| Alan Stocks | John Batley | 1 |
| Andrew Whipp | Warren Dyden | 1 |
| Amy Cudden | Grace Bishop | 1 |
| Richard Short | Neville Furness | 1 |
| Emily Taaffe | Janna Jeffries | 1 |
| Julia Ford | Morven | 1 |
| George Costigan | Bill Telling | 1 |
| Kojo Attah | Lock Forward | 1 |
| Maureen Beattie | Dr Vivienne Ripman | 1 |
| John Hollingworth | PC Shawn Turnly | 1 |
| Kathryn Pogson | Vanessa Gartside | 1 |
| Daniel Weyman | Jim Briscoe | 1 |
| Mawaan Rizwan | Jamil | 1 |
| Gordon Kennedy | Eddie | 1 |
| Leemore Marrett Jr. | Dash | 1 |
| Sharon Duce | Marcia | 1 |
| Ben-Ryan Davies | Harris | 1 |
| Patrick Robinson | Royce Hobson | 1 |
| Katy Carmichael | Gayle Beecher | 1 |
| Asan N'Jie | Simon Whenchurch | 1 |
| Sian Webber | Glenda McMann | 1 |
| Jodie McNee | Natalie Webb | 1 |
| Su Elliot | Bron Martin | 1 |
| Su Elliot | Irene Francis | 1 |
| Lolita Chakrabarti | Caroline Fletcher | 1 |
| Angela Bruce | Beryl Doyle | 1 |
| Niek Versteeg | Paul | 1 |
| Nicholas Lumley | Derek | 1 |
| Kaye Brown | Dorothy Elmsworth | 1 |
| Robert Morgan | Donald Colley | 1 |
| Ezra Faroque Khan | Hisham Kalb | 1 |
| Mairead McKinley | Rene O'Brien | 1 |
| Barry Aird | Darren Tripp | 1 |
| Karen Bryson | Louise Wilmott | 1 |
| Ene Frost | Father Paul | 1 |
| Lu Corfield | Jo Travers | 1 |
| Jacqueline Boatswain | Sarah Ashers | 1 |
| Annabel Leventon | Margaret Kraszewski | 1 |
| Rick Warden | Declan Webley | 1 |
| Joanna Horton | Kate Burns | 1 |
| Rina Mahoney | Aliah Kapoor | 1 |
| Jamie Ballard | Duncan Maxwell | 1 |
| Katie Clarkson-Hill | Jade | 1 |
| Jake Fairbrother | Macca | 1 |
| Iola Evans | Phoebe Dwyer | 1 |
| Pippa Bennett-Warner | Soeur Claire | 1 |
| Michael Shaeffer | Ian Holland | 1 |
| Shelley Williams | Sophie Blackstock | 1 |
| Joe Blakemore | Peter / Tom | 1 |
| Tachia Newall | Ben | 1 |
| Caroline Loncq | Anna Marshbrook | 1 |
| Marian McLoughlin | Tina Tripp | 1 |
| Joshua Hill | PC Mike Randall | 1 |
| Katie Lyons | Tina Callow | 1 |
| Michael Begley | Jason Hay | 1 |
| Ayoola Smart | Lucy Curran | 1 |
| Greg Kolpakchi | Goran Vlasic | 1 |
| Natalie Ann Jamieson | Karen | 1 |
| Elizabeth Edmonds | Mary Winter | 1 |
| Tanya Franks | Lorraine Hallam | 1 |
| Jessica Baglow | Ronnie Bennions | 1 |
| Katherine Rose Morley | Claire Viner | 1 |
| Flo Wilson | Social worker | 1 |
| Georgia Maguire | Vicki Hogarth | 1 |
| Megan Purvis | Eva Pinnock | 1 |
| Vicky Hall | Sonia Brock | 1 |
| Kemi-Bo Jacobs | Claire Tovey | 1 |
| Mica Ricketts | Liza Conney | 1 |
| Robert Blythe | Bob Tate | 1 |
| Catherine Bailey | Katy Turner | 1 |
| Michael Balogun | Lee Millworth | 1 |
| Philip Hill-Pearson | Lee Stonnall | 1 |
| Ciarán Griffiths | Steve Stonnall | 1 |
| Sian Reese-Williams | Beth Draper | 1 |
| Lizzie Hopley | Deb Kingston | 1 |
| Jack Ellis | Brian Hallam | 1 |
| Stuart Laing | Rob Bayliss | 1 |
| Elizabeth Rider | Eileen Hennings | 1 |
| John Harding | Dr. Julian Moore | 1 |
| Oliver Wellington | Jack Marshbrook | 1 |
| Steve Lorrigan | Alun Wilmott | 1 |
| Wil Johnson | Gary Whenchurch | 1 |
| Danny Horn | Ben Marsh | 1 |
| Anthony Barclay | Alan Randle | 1 |
| Derek Hutchinson | Jeb Branning | 1 |
| Joshua J. Parker | Joshua Heslop | 1 |
| Roland Oliver | Edwin Short | 1 |
| Annie Hulley | Diane Weaver | 1 |
| Charlie Hardwick | Grace Webley | 1 |
| Sean McKenzie | George Everitt | 1 |
| Paul Courtenay Hyu | Huang | 1 |
| Denver Isaac | Dylan Sharpe | 1 |
| Liam Ainsworth | Rich | 1 |
| George Bukhari | Gareth Wyatt | 1 |
| Sudha Bhuchar | Aisha Sharma | 1 |
| Florian Ghimpu | Janusz Hiszpanski | 1 |
| Nikita Mehta | Naz Singh | 1 |
| Ben Addis | David Gilloway | 1 |
| Grace Hogg-Robinson | Zara Swann | 1 |
| Flynn Allen | Lyle Channing | 1 |
| Claire Rafferty | Ellie Connock | 1 |
| Jake Lawson | Joe Mallon | 1 |
| Frieda Thiel | Roxy | 1 |
| Caolan Byrne | Eric Hurst | 1 |
| Amir Boutrous | Malik Saleh | 1 |
| Michael Feast | Leonard Sidden | 1 |
| Alex Childs | Kirsty Hopkins | 1 |
| Daniel-John Williams | Fineus Walsh | 1 |
| Rod Arthur | Jackie Nolan | 1 |
| Kellie Bright | Vanessa Barnes | 1 |
| John Rowe | Percy Monkford | 1 |
| Lorraine Bruce | Carmel Sumner | 1 |
| Michelle Tate | Shona Adams | 1 |