| Name | Character | Episodes |
|---|---|---|
| Rita Russek | Anna Springer | 106 |
| Leonard Lansink | Georg Wilsberg | 105 |
| Oliver Korittke | Ekkehardt Talkötter | 95 |
| Johanna Klante | Lilly | 2 |
| Barnaby Metschurat | Jens Gerber | 2 |
| Maximilian von Pufendorf | Sigbert Grahnke | 2 |
| Franziska Walser | Katharina | 2 |
| Walter Kreye | Walter Grahnke | 2 |
| Katrin Pollitt | 2 | |
| Marie Zielcke | Tanja | 2 |
| Hanno Friedrich | Philipp Assmann | 2 |
| Götz Schubert | Landau | 2 |
| Lavinia Wilson | Tessa Harderer | 1 |
| Tom Wlaschiha | Stefan Wehnert | 1 |
| Waldemar Kobus | Kaplan | 1 |
| Waldemar Kobus | Dekan Braun | 1 |
| Dietmar Mues | Prior Elijah | 1 |
| Dietmar Mues | Karl von Havenbroich | 1 |
| Antje Schmidt | Vera Lemberg | 1 |
| Stefan Gubser | Dr. Baumgartner | 1 |
| Birge Schade | Marion Brinkhoff | 1 |
| Tom Beck | Ingo Bundschuh | 1 |
| Barbara Rudnik | Ines | 1 |
| Hannes Hellmann | Christian Klarman | 1 |
| Monica Bleibtreu | Waltraud Rehmer | 1 |
| Dirk Martens | Tillmann Drösser | 1 |
| Kirsten Block | Christa Sieland | 1 |
| Florian Panzner | Michael Bach | 1 |
| Rolf Hoppe | Erwin Kuhn | 1 |
| Godehard Giese | Daniel Kaiser | 1 |
| Godehard Giese | Oliver Brandstetter | 1 |
| Julia Dietze | Claudine Carrier | 1 |
| Martin Brambach | Torsten Schmitt | 1 |
| Martin Brambach | Til Geskamp | 1 |
| Roman Knižka | Jan Faber | 1 |
| Andreas Pietschmann | Ingo Vogt | 1 |
| Gesine Cukrowski | Helen Lobland | 1 |
| Leslie Malton | Juliane Kuhn | 1 |
| Leslie Malton | Medical Officer | 1 |
| Claudia Michelsen | Melanie Rensing | 1 |
| Michael Kessler | Traffic Officer | 1 |
| Eva Löbau | Ulla Falkenberg | 1 |
| Rainer Bock | Müntemeyer | 1 |
| Jorres Risse | Tschakko | 1 |
| Peter Kurth | Karsten Scherer | 1 |
| Christian Redl | Debelius | 1 |
| Anian Zollner | Hartmann | 1 |
| Saskia Vester | Franziska | 1 |
| Sönke Möhring | Gerd Ridderbusch | 1 |
| Aljoscha Stadelmann | Steffen Weber | 1 |
| Marc Hosemann | Dr. Vermellen | 1 |
| Alexander Radszun | Uwe Schlachkamp | 1 |
| Elena Uhlig | Marie Kaiser | 1 |
| Karin Anselm | Wilma Pobradt | 1 |
| Detlef Bothe | Skipper Rasmussen | 1 |
| Wanja Mues | Dr. Haus | 1 |
| Rolf Kanies | Herbert Schering | 1 |
| Rolf Kanies | Heinrich Brandstetter | 1 |
| Katja Studt | Katharina | 1 |
| Katja Studt | Kamilla Marks | 1 |
| Angela Roy | Maria von Havenbroich | 1 |
| Jürgen Rißmann | Norbert Hillmann | 1 |
| David C. Bunners | Rolf Specker | 1 |
| Philipp Moog | Markus Faber | 1 |
| Lilia Lehner | Receptionist | 1 |
| Daniel Zillmann | Detlef | 1 |
| Xenia Assenza | Yasmin | 1 |
| Wilfried Hochholdinger | Greinert | 1 |
| Burghart Klaußner | Gunnar Weltenbrink | 1 |
| Thomas Arnold | Felix Berning | 1 |
| Peter Sattmann | Mario | 1 |
| Bernd Michael Lade | Enno Fellner | 1 |
| Arndt Schwering-Sohnrey | Antonius | 1 |
| Vijessna Ferkic | Rebecca | 1 |
| Susanna Simon | Nikola Füsting | 1 |
| Udo Schenk | Mr. Koch | 1 |
| Harald Schrott | Benjamin Frehse | 1 |
| Johann von Bülow | Gordon Haller | 1 |
| Thomas Limpinsel | Labuske | 1 |
| André Hennicke | Pater Gabriel | 1 |
| Jochen Nickel | 1 | |
| Marco Hofschneider | Hagen von Unger | 1 |
| Jeanette Hain | Johanna Eckelt | 1 |
| Melika Foroutan | Karla Berhenke | 1 |
| Aleksandar Jovanović | Oswald | 1 |
| Rebecca Immanuel | Karin | 1 |
| Rebecca Immanuel | Dorith Magunsky | 1 |
| Tina Ruland | Ms. Mayerhofer | 1 |
| Christoph M. Ohrt | Michael Lobland | 1 |
| Constantin von Jascheroff | Jörn Bakker | 1 |
| Anna Brüggemann | Franziska Upholt | 1 |
| Katharina Müller-Elmau | Andrea Seekatz | 1 |
| Stefan Weinert | Nachtweyh | 1 |
| Sabine Vitua | Marion Hartwig | 1 |
| Michael Kind | Martin Henne | 1 |
| Vladimir Burlakov | Marvin Berg | 1 |
| Bernhard Schütz | Bohlsen | 1 |
| Mareike Fell | Gitty Konrad | 1 |
| Hans Martin Stier | Merschmann | 1 |
| Christine Schorn | Ilse Fellner | 1 |
| Uwe Rohde | Bernhard | 1 |
| Bernadette Heerwagen | Sabine Wandchen | 1 |
| Ronald Kukulies | Winfried Bielefeld | 1 |
| Marek Harloff | Niels Schiffer | 1 |
| Gustav Schmidt | Linus Gerlach | 1 |
| Michael Grimm | Dede | 1 |
| Stefan Reck | Jeremiah | 1 |
| Stephan Kampwirth | Thomas Rensing | 1 |
| Stephan Kampwirth | Timm Thake | 1 |
| Anja Kruse | Lea Sonnenborn | 1 |
| Bela B. | Galerist Biereichel | 1 |
| August Schmölzer | Richard Buchholz | 1 |
| Peter Davor | Karsten Breiderhoff | 1 |
| Markus Knüfken | Pfarrer Albers | 1 |
| Steffen Münster | Dr. Suhlke | 1 |
| Sarah Alles | Isabel Wolfangel | 1 |
| Heike Trinker | Ms. Seeberg | 1 |
| Heike Trinker | Sabine Morgenstern | 1 |
| David Scheller | Lothar | 1 |
| Tobias Oertel | Thomas Winter | 1 |
| Thomas Bestvater | Harry Keitel | 1 |
| Sylta Fee Wegmann | Ramona Liek | 1 |
| Sabine Berg | Mechthild Kerstenbrock | 1 |
| Hugo Egon Balder | Robert Schönsee | 1 |
| Tamara Simunovic | Sonja | 1 |
| Patrick von Blume | Wolfgang Kohlmann | 1 |
| Patrick von Blume | Uhlenbrock | 1 |
| Janette Rauch | Lena Schwab | 1 |
| Michael Kausch | Albert Pauly | 1 |
| Wichart von Roëll | Passlick's Father-in-Law | 1 |
| Cay Helmich | Gesine Schlacke | 1 |
| Uwe Preuss | Manfred Buckebrede | 1 |
| Lale Yavaş | Maike Lehmann | 1 |
| Patricia Meeden | Dr. Tessa Tilker | 1 |
| Michael Mendl | Walter Moorwessel | 1 |
| Michael Lott | Wolfgang Schwendter | 1 |
| Frederick Lau | Ludger Schmitz | 1 |
| Lambert Hamel | Lothar Dörner | 1 |
| Nils Nelleßen | Lars Jüssen | 1 |
| Finja Martens | Johanna Landau | 1 |
| Jürgen Tarrach | Guido Haffner | 1 |
| Sonsee Neu | Anette von Bülow | 1 |
| Mignon Remé | Irmgard Köhler | 1 |
| Stefan Kurt | Dr. Stegner | 1 |
| Florentine Lahme | Silke Buschfeld | 1 |
| Thomas Sarbacher | Heiner Lemberg | 1 |
| Johanna Gastdorf | Ms. Brügge | 1 |
| Peter Fitz | Kurt Vosswinkel | 1 |
| Bernd Stegemann | Horst Große-Eschhaus | 1 |
| Jochen Kolenda | 1 | |
| Oliver Wnuk | Rolf Blank | 1 |
| Tim Wilde | Oliver Maaß | 1 |
| Nils Brunkhorst | Michael Klarmann | 1 |
| Max Giermann | Felix | 1 |
| Torsten Michaelis | Blinder Egon | 1 |