| Name | Character | Episodes |
|---|---|---|
| Stephen Tompkinson | Capitaine Alan Banks | 30 |
| Jack Deam | Lieutenant Ken Blackstone | 30 |
| Andrea Lowe | Lieutenant Annie Cabbot | 30 |
| Caroline Catz | Capitaine Helen Morton | 24 |
| Lorraine Burroughs | Winsome Jackman | 12 |
| Samuel Anderson | Vince Grady | 6 |
| Badria Timimi | Dr. Allen | 4 |
| Charlotte Riley | Lucy Payne | 2 |
| Charlie Heaton | Gary McCready | 2 |
| Christine Bottomley | Katy Heath | 2 |
| Alice Henley | Maddy Phillips | 2 |
| John Lightbody | Paul Cain | 2 |
| Rick Warden | Mark Campbell | 2 |
| Oliver Woollford | Kyle Heath | 2 |
| Monica Dolan | Maggie Forrest | 1 |
| Colin Tierney | Chief Supt Gerry Rydell | 1 |
| John Light | Mark Keane | 1 |
| Tamzin Merchant | Miranda Aspern | 1 |
| Michael Maloney | Malcolm Austin | 1 |
| Samuel Roukin | Marcus Payne | 1 |
| Rakhee Thakrar | Lab Assistant | 1 |
| Sian Breckin | PC Janet Taylor | 1 |
| Michael Keogh | PC Dennis Morrisey | 1 |
| Raquel Cassidy | Dr. Elizabeth Waring | 1 |
| Barry Sloane | Jackie Wray | 1 |
| John Bowe | Dr. Patrick Aspern | 1 |
| Olivia Popica | Angela Petri | 1 |
| Anna Wilson-Jones | Rosalind Rydell | 1 |
| Steven Elder | Dr. Patterson | 1 |
| Ian Bartholomew | Timothy Randall | 1 |
| Gary Cargill | Jake McMahon | 1 |
| Don Gilet | 0 | |
| Stephen Tompkinson | Inspector Alan Banks | 0 |
| Micah Balfour | 0 |