| Name | Character | Episodes |
|---|---|---|
| Dieter Pfaff | Dr. Maximilian Bloch | 24 |
| Johanna Gastdorf | Martina | 2 |
| Adrian Topol | Josef | 1 |
| Antje Schmidt | Ärztin | 1 |
| Matthias Habich | Martin Weidner | 1 |
| Birge Schade | Sabine Doran | 1 |
| Devid Striesow | Henny Fiedler | 1 |
| Devid Striesow | Jens | 1 |
| Hanns Zischler | Claus Claussen | 1 |
| Tom Schilling | Paul Seifert | 1 |
| Nina Hoss | Lilly | 1 |
| Kirsten Block | 1 | |
| Kirsten Block | Judith Rode | 1 |
| Holger Handtke | Schöneberg | 1 |
| Lisa Maria Potthoff | Jenni Haller | 1 |
| Filip Peeters | Filip de Keyzer | 1 |
| Claudia Michelsen | Marianne Herbst | 1 |
| Eva Löbau | Heike Liebknecht | 1 |
| Rainer Bock | Klaus Hollstein | 1 |
| Anna Maria Mühe | Stefanie Rudolf | 1 |
| Karin Baal | Frau Köster | 1 |
| Birgit Minichmayr | Andrea | 1 |
| Alice Dwyer | Tina Rode | 1 |
| Anna Fischer | Meret Zimmermann | 1 |
| Rosemarie Fendel | Mia Claussen | 1 |
| Simon Verhoeven | 1 | |
| Florian Bartholomäi | Lasse / Lukas Hilversum | 1 |
| Eleonore Weisgerber | Margarete Haller | 1 |
| Lena Stolze | Mutter Elisabeth | 1 |
| Ursula Werner | Svenjas Adoptivmutter | 1 |
| Vadim Glowna | Lorenz Haller | 1 |
| George Lenz | 1 | |
| Rudolf Kowalski | Albert Unbekannt | 1 |
| Arndt Schwering-Sohnrey | Martin Morlock | 1 |
| Susanne Lothar | Daniela Sonnenberg | 1 |
| Katharina Schüttler | Rieke Hollstein | 1 |
| Petra Zieser | 1 | |
| Catherine Flemming | Clara Born | 1 |
| Tilo Prückner | Ludwig Schulze | 1 |
| Jochen Nickel | Frank Rode | 1 |
| Aylin Tezel | Dalia Feisal | 1 |
| Katrin Sass | Hannah | 1 |
| Adriana Altaras | Halimah Omer | 1 |
| Arnd Klawitter | Dr. Kellner | 1 |
| Christine Schorn | Frau Mangold | 1 |
| Inka Friedrich | Sasika | 1 |
| Margarita Broich | Petra Engelhardt | 1 |
| Erni Mangold | Großmutter Johanna | 1 |
| Christian Näthe | Benno Pflüger | 1 |
| Piet Fuchs | Peter | 1 |
| André Jung | Dieter Hilversum | 1 |
| Astrid Meyerfeldt | Gesa Rudolf | 1 |
| Götz Burger | Prof. Dr. Sievers | 1 |
| Heike Trinker | Inga | 1 |
| Nele Mueller-Stöfen | Nina | 1 |
| Uwe Preuss | Pfölzer | 1 |
| Tilo Nest | Martin Hellmann | 1 |
| Daniele Rizzo | Murat | 1 |
| Anna Bullard | Aven Carlington | 1 |
| Michael Mendl | Josef Klettenberg | 1 |
| Guntbert Warns | Herr Born | 1 |
| Henning Peker | Vater bei Elternabend | 1 |
| Rainer Sellien | Michael Doran | 1 |
| Anna Böger | Kommisarin Jule Möller | 1 |
| Peter Jordan | Stefan | 1 |
| Dagmar Manzel | Heide Welk | 1 |
| Christian Schaefer | 1 | |
| Carlo Ljubek | Kai Rieger | 1 |