| Name | Character | Episodes |
|---|---|---|
| Carlos Lacámara | Paco Ortiz | 68 |
| Ada Maris | Gina Cuevas | 68 |
| Arnetia Walker | Nurse Annie Roland | 68 |
| Kip Gilman | Dr. Hank Kaplan | 68 |
| David Rasche | Jack Trenton | 46 |
| Stephanie Hodge | Nurse Sandy Miller | 46 |
| Markus Flanagan | Luke Fitzgerald | 24 |
| Loni Anderson | Casey MacAfee | 22 |
| Florence Stanley | Dr. Amanda Riskin | 22 |
| Jeff Altman | Greg Vincent | 22 |
| Leslie Jordan | 2 | |
| Adam West | 1 | |
| Eric Pierpoint | 1 | |
| Stuart Pankin | 1 | |
| Amy Hill | 1 | |
| Richard Burgi | 1 | |
| Tim Thomerson | 1 | |
| Tom Virtue | 1 | |
| Ed McMahon | 1 | |
| Rue McClanahan | Blanche Devereaux | 1 |
| Joe Alaskey | 1 | |
| Vanessa Marquez | Angelica | 1 |