| Name | Character | Episodes |
|---|---|---|
| Rebecca Ferguson | Elizabeth Woodville | 10 |
| Tom McKay | Jasper Tudor | 10 |
| Juliet Aubrey | Anne Beauchamp | 10 |
| Janet McTeer | Jacquetta of Luxembourg | 10 |
| Max Irons | Edward IV of England | 10 |
| James Frain | Richard Neville | 10 |
| Eleanor Tomlinson | Isabel Neville | 10 |
| Rupert Graves | Thomas Stanley | 10 |
| Michael Maloney | Henry Stafford | 10 |
| Aneurin Barnard | Richard III of England | 10 |
| Faye Marsay | Anne Neville | 10 |
| Amanda Hale | Margaret Beaufort | 10 |
| Caroline Goodall | Cecily Neville | 10 |
| David Oakes | George Plantagenet | 10 |
| Ben Lamb | Anthony Woodville | 10 |
| Eve Ponsonby | Mary Woodville | 10 |
| Otto Farrant | Thomas Grey | 5 |
| Dean-Charles Chapman | Richard Grey | 4 |
| Elinor Crawley | Cecily of York | 3 |
| Shaun Dooley | Robert Brackenbury | 3 |
| Pixie Davies | Elizabeth of York | 3 |
| Leo Bill | Reginald Bray | 3 |
| Emily Berrington | Jane Shore | 3 |
| Frances Tomelty | Margaret Beauchamp | 3 |
| Freya Mavor | Elizabeth of York | 3 |
| Ted Allpress | Richard of Shrewsbury | 3 |
| Oscar Kennedy | Henry VII of England | 3 |
| Hugh Mitchell | Richard Welles | 2 |
| Madeleine Harris | Margaret of York | 2 |
| Robert Pugh | Richard Woodville | 2 |
| Joey Batey | Edward of Westminster | 2 |
| Michael Jenn | Dr. Lewis | 2 |
| Arthur Darvill | Harry Stafford | 2 |
| Simon Ginty | John Neville | 2 |
| Eloise Webb | Elizabeth of York | 2 |
| Veerle Baetens | Margaret of Anjou | 2 |
| Elsa Houben | Katherine Woodville | 2 |
| Rudi Goodman | Richard Grey | 2 |
| Nick Hendrix | Edmund Beaufort | 1 |
| Lizzy McInnerny | Lady Sutcliffe | 1 |
| Joren Seldeslachts | Charles the Bold | 1 |
| Martin Turner | Archbishop | 1 |
| Guy Flanagan | James Friars | 1 |