| Name | Character | Episodes |
|---|---|---|
| Katharina Böhm | Vera Lanz | 96 |
| Jürgen Tonkel | Paul Böhmer | 96 |
| Martin Umbach | Karsten Seitz | 6 |
| Stephan Kampwirth | Marc Berger | 4 |
| Oliver Stokowski | Stefan Hartig | 3 |
| Christoph Schechinger | Maximilian Murnau | 3 |
| Mišel Matičević | Mario Fechter | 2 |
| Sabine Vitua | Monique Küster | 2 |
| Lavinia Wilson | Jutta Baumann | 1 |
| Waldemar Kobus | Christian Franke | 1 |
| Katharina Nesytowa | Darja Ionescu | 1 |
| Michael Roll | Christian Helmes | 1 |
| Ursula Strauss | Hanna Böhmer | 1 |
| Birge Schade | Regina Stäber | 1 |
| Hannes Hellmann | Egon Fiedler | 1 |
| Suzan Anbeh | Hannah Eichner | 1 |
| Luise Heyer | Simone Aigner | 1 |
| Mišel Matičević | Mario Fechtner | 1 |
| Peri Baumeister | Jessica Kempf | 1 |
| Dirk Martens | Ernst Zacher | 1 |
| Kirsten Block | Monika Aigner | 1 |
| Mehdi Nebbou | Cristian Farron | 1 |
| Florian Panzner | Torben Segeberger | 1 |
| Julia Dietze | Julia Becker | 1 |
| Martin Brambach | Eduard Blank | 1 |
| Roman Knižka | Dr. Wollinger | 1 |
| Andreas Pietschmann | Amar Lukic | 1 |
| Andreas Pietschmann | Karl-Heinz Bessler | 1 |
| Martin Gruber | Theo Koschwitz | 1 |
| David Bredin | Jannis Strecker | 1 |
| Julian Looman | Alexander Kant | 1 |
| Jorres Risse | Chris Oelschläger | 1 |
| Kida Khodr Ramadan | Hassan Bürok / Sahid | 1 |
| Christian Redl | Josef Köhler | 1 |
| Anian Zollner | Dr. Malte Leiss | 1 |
| Thure Riefenstein | Holger Buresch | 1 |
| Rike Schmid | Gina Petri | 1 |
| Alice Dwyer | Jessica Dieskamp | 1 |
| Gaby Dohm | Gerda Boltinger | 1 |
| Jürgen Vogel | Robert Heffler | 1 |
| Hary Prinz | Max Freisinger | 1 |
| Alexander Held | Karl-Walter von Stetten | 1 |
| Alexander Held | Wilfried Koch | 1 |
| Michael König | Lambert Eichner | 1 |
| Erdal Yıldız | Ramasan | 1 |
| Alexander Radszun | Josef Ried | 1 |
| Florian Bartholomäi | Oskar von Stetten | 1 |
| Wanja Mues | Toni Marschaber | 1 |
| Susanne Bormann | Anke Kreutzer | 1 |
| Susanne Bormann | Sonja Denninger | 1 |
| Sophie von Kessel | Janneke Blumberg | 1 |
| Sophie von Kessel | Karin Berger | 1 |
| Lena Stolze | Anne Probst | 1 |
| Barnaby Metschurat | Felix Jung | 1 |
| Andreas Schmidt | Gernot Viehweg | 1 |
| Ella-Maria Gollmer | Maggie Heinkel | 1 |
| Maximilian von Pufendorf | Marc Förster | 1 |
| Janna Striebeck | Liane Bayer | 1 |
| Deborah Kaufmann | Anett Bachmaier | 1 |
| Gregor Bloéb | Robert Hartung | 1 |
| Isolde Barth | Elsa Koschwitz | 1 |
| Johannes Franke | Marco Rossi | 1 |
| Philipp Moog | Walther Rettinger | 1 |
| George Lenz | Anwalt Kaltenbrink | 1 |
| Ercan Durmaz | Philipp Gera | 1 |
| Murali Perumal | Dr. Hassan Adi | 1 |
| Jan Henrik Stahlberg | Xaver Baumgartner | 1 |
| Wilfried Hochholdinger | Till Sammer | 1 |
| Niels-Bruno Schmidt | Hans Gast | 1 |
| Rudolf Kowalski | Jürgen Behnke | 1 |
| Milton Welsh | Jürgen Weidner | 1 |
| Dennis Mojen | Julian Schröder | 1 |
| Petra Zieser | Hanna Förster | 1 |
| Dieter Mann | Wilhelm Brockhausen | 1 |
| Susanna Simon | Insa Wilde | 1 |
| Erika Marozsán | Melissa Thalberg | 1 |
| Harald Schrott | Dr.Brandt | 1 |
| Johann von Bülow | Ulrich Neumann | 1 |
| Johann von Bülow | René Mosbacher | 1 |
| Thomas Limpinsel | Rainer Franke | 1 |
| André Hennicke | Frank 'Franko' Holzinger | 1 |
| Jochen Nickel | Charles Schwesig | 1 |
| Walter Kreye | Anton Schleimann | 1 |
| Bibiana Beglau | Beate Lukaschek | 1 |
| Melika Foroutan | Petra Blum | 1 |
| David Rott | Maik Grasser | 1 |
| Lars Rudolph | Uwe Roberts | 1 |
| Stefan Konarske | Peter Lichter | 1 |
| Peter Schneider | Jakob Wiese | 1 |
| Martin Rapold | Hannes De Boer | 1 |
| Julia Brendler | Andrea Bechtholt | 1 |
| Arnd Klawitter | Dr. Andreas Sindberg | 1 |
| Inka Friedrich | Marie Ziebig | 1 |
| Jennifer Ulrich | Netty Dühr | 1 |
| Marek Harloff | Marius Jankowski | 1 |
| Wolfgang Fierek | Anton Reiter | 1 |
| Julius Nitschkoff | Jakob Wächter | 1 |
| Isolda Dychauk | Lea Bartels | 1 |
| Heio von Stetten | Stefan Meiwald | 1 |
| Michael Grimm | Franz Jacobi | 1 |
| Michael Grimm | Eberhard Hallhuber | 1 |
| Lara-Joy Körner | Kerstin Gera | 1 |
| Nicole Marischka | Heike Steinbeck | 1 |
| Norman Hacker | Hausmeister | 1 |
| Norman Hacker | Georg Friedmann | 1 |
| André Jung | Benno Wiese | 1 |
| Maria Bachmann | Maike Seitz | 1 |
| Maximilian Grill | Alexander Stockum | 1 |
| Maria Schrader | Johanna Leonhard | 1 |
| Robinson Reichel | Seidel | 1 |
| Hans-Uwe Bauer | Helmut Schabinsky | 1 |
| Sigi Zimmerschied | Gero Hoffmann | 1 |
| Hansa Czypionka | Franz Koschwitz | 1 |
| Götz Burger | Herr Zirner | 1 |
| Peter Knaack | Horst Jahnke | 1 |
| Emilio De Marchi | Dr.Berthold | 1 |
| Max Hegewald | Max Koch | 1 |
| Dirk Borchardt | Arthur Meyer | 1 |
| Patrick von Blume | Fritz Garber | 1 |
| Lucas Prisor | Calvin Bauer | 1 |
| Andreas Patton | Marcel Richter | 1 |
| Stefan Merki | Herbert Stadler | 1 |
| Waléra Kanischtscheff | Jefim | 1 |
| Michael Kausch | 1 | |
| Cem-Ali Gültekin | Iliyas Demir | 1 |
| Gerdy Zint | Piet van Meeren | 1 |
| David Paryla | Rettungssanitäter | 1 |
| Max Felder | Jonas Gemmer | 1 |
| Christian Schaeffer | Werner Maurer | 1 |
| Cornelia Gröschel | Apothekerin | 1 |
| Sebastian Weber | Harald Kutka | 1 |
| Cornelia Ivancan | Sandra Niedermeyer | 1 |
| Jörg Witte | Lars Zander | 1 |
| Francis Fulton-Smith | Mathias Schönauer | 1 |
| Athena Strates | Michelle Seibert | 1 |
| Michael Lott | Franz Heinkel | 1 |
| Heikko Deutschmann | Hannes Walther | 1 |
| Tilman Strauss | Dominik Haas | 1 |
| Milan Peschel | Markus Gärtner | 1 |
| Simon Pearce | Apotheker | 1 |
| Lisa Vicari | Vanessa Willski | 1 |
| Rainer Sellien | Thorsten Wächter | 1 |
| Götz Schubert | Anton Ziebig | 1 |
| Florian Stetter | Christian Probst | 1 |
| Maximilian Simonischek | Georg Steinbach | 1 |
| Felix Klare | Holger Baumann | 1 |
| Axel Pape | Hanskarl Demke | 1 |
| Simon Schwarz | Andy Berlinger | 1 |
| Sonsee Neu | Margarethe Schmidt | 1 |
| Mac Steinmeier | Otto Wasner | 1 |
| Johanna Bittenbinder | Nicole Borchardt | 1 |
| Fritz Karl | Mischa Landauer | 1 |
| Thomas Sarbacher | Markus Schüttler | 1 |
| Mario Irrek | 1 | |
| Johanna Gastdorf | Charlotte Lichter | 1 |
| Thomas Huber | Dr. Lorenz Legband | 1 |
| Carolina Vera | Johanna Dierach | 1 |
| Jurij Rosstalnyj | Danil Suckow | 1 |
| Rudolf Krause | Jens Dürschlag | 1 |
| Falk Rockstroh | Stefan Probst | 1 |
| Tim Wilde | Janis Kuschel | 1 |
| Oliver Stritzel | Eberhardt Kaminsk | 1 |
| Juliane Köhler | Liane Koch | 1 |