| Name | Character | Episodes |
|---|---|---|
| Timothy Hutton | Russ Skokie | 11 |
| Benito Martinez | Alonzo Gutiérrez | 11 |
| Penelope Ann Miller | Eve Carlin | 11 |
| Felicity Huffman | Barb Hanlon | 11 |
| W. Earl Brown | Tom Carlin | 11 |
| Caitlin Gerard | Aubry Taylor | 11 |
| Richard Cabral | Hector Tontz | 11 |
| Elvis Nolasco | Carter Nix | 11 |
| Johnny Ortiz | Tony Gutiérrez | 11 |
| Timothy Hutton | Dan Sullivan | 10 |
| Regina King | Terri LaCroix | 10 |
| Felicity Huffman | Leslie Graham | 10 |
| Connor Jessup | Taylor Blaine | 10 |
| Trevor Jackson | Kevin LaCroix | 10 |
| Lili Taylor | Anne Blaine | 10 |
| Elvis Nolasco | Chris Dixon | 10 |
| Angelique Rivera | Evy Dominguez | 10 |
| Regina King | Aliyah Shadeed | 9 |
| Timothy Hutton | Nicholas Coates | 8 |
| Regina King | Kimara Walters | 8 |
| Benito Martinez | Luis Salazar | 8 |
| Felicity Huffman | Jeanette Hesby | 8 |
| André 3000 | Michael LaCroix | 8 |
| Connor Jessup | Coy Henson | 8 |
| Lili Taylor | Clair Coates | 8 |
| Richard Cabral | Isaac Castillo | 8 |
| Joe Nemmers | Rick Soderbergh | 8 |
| Emily Bergl | Lilah Tanner | 7 |
| Todd Terry | Jackson | 7 |
| Faran Tahir | Rhys Bashir | 6 |
| Hope Davis | Steph Sullivan | 6 |
| Lili Taylor | Nancy Straumberg | 6 |
| Jennifer Savidge | Ruth Taylor | 6 |
| Emily Warfield | Lisa | 5 |
| Richard Cabral | Sebastian De La Torre | 5 |
| Taylor John Smith | Luke | 4 |
| Jesse Borrego | Oscar | 4 |
| Julian Works | Edgar | 4 |
| Gwendoline Yeo | Richelle | 4 |
| Stephanie Sigman | Monica Salazar | 3 |
| David DeLao | George Fierro | 3 |
| Marlyne Barrett | Chris Thompson | 2 |
| Marshall R. Teague | Ben Callahan | 2 |
| J. J. Soria | Luis | 2 |
| Lily Knight | Colleen Sherrod | 2 |
| Keith Bogart | Grell | 2 |
| Jon Michael Davis | Detective Sanderson | 2 |
| Joe Nemmers | Anderson | 2 |
| Hugo Perez | Robles | 2 |
| Damon Carney | Don Wheeler | 2 |
| Benito Martinez | Dominic Calderon | 1 |
| Darryl Cox | Evan Barry | 1 |
| Jason Douglas | Hess | 1 |
| Brent Sexton | Tommy | 1 |
| Jason Liebrecht | Mark (voice) | 1 |
| Jason Liebrecht | Scott | 1 |
| Van Quattro | Marquot | 1 |
| Daniel Louis Rivas | Tejo | 1 |
| Scott Takeda | Mike Narasaki | 1 |
| Kathy Rose Center | Woman Customer | 1 |
| Blaise Miller | Segment Producer | 1 |
| Holt Boggs | Patrol Officer | 1 |
| Jack Watkins | Darrel | 1 |