| Painkiller Jane is an American-Canadian science fiction and action television series based on the comic book character of the same name. Airing on the Sci Fi Channel in the US starting April 13, 2007 and Global in Canada, it starred Kristanna Loken as the titular character. On August 15, 2007, it was canceled after one season of 22 episodes. |
| Name | Character | Episodes |
|---|---|---|
| Kristanna Loken | Jane Vasco | 22 |
| Rob Stewart | Andre McBride | 22 |
| Stephen Lobo | Seth Carpenter | 22 |
| Sean Owen Roberts | Riley Jensen | 22 |
| Noah Dalton Danby | Connor King | 22 |
| Alaina Huffman | Maureen Bowers | 12 |
| John Reardon | Brian | 9 |
| Nathaniel DeVeaux | Joe Waterman | 7 |
| Tiera Skovbye | Jane - 10 Years Old | 3 |
| Tom Butler | Dr. John Roberts | 2 |
| Adrian Holmes | Steve Ford | 2 |
| Melanie Papalia | Amanda Worth | 2 |
| Meghan Ory | Wanda | 1 |
| Garwin Sanford | 1 | |
| Megan Charpentier | Little Girl | 1 |
| Karen Kruper | 1 | |
| Ken Tremblett | 1 | |
| Barbara Tyson | 1 | |
| Elias Toufexis | 1 | |
| Sonya Salomaa | 1 | |
| David Richmond-Peck | 1 | |
| Dominic Zamprogna | 1 | |
| Emy Aneke | 1 | |
| Jody Thompson | 1 | |
| Paul Anthony | 1 | |
| Sonja Bennett | Stacey | 1 |