| Growing up in a family of physicians, Tan Yun Xian was adored by her grandparents for her intellect, curiosity and medical acumen. Despite the many barriers for female physicians in ancient China, Yun Xian nevertheless proved herself to be a skilled family and female doctor — and ultimately the most famous female doctor of the Ming Dynasty. |
| Name | Character | Episodes |
|---|---|---|
| Leo Wu | Young Zhu Jian Shen | 50 |
| Jin Chen | Wang Meilin | 50 |
| Liu Shishi | Tan Yun Xian | 50 |
| Huang Xuan | Zhu Qi Yu | 50 |
| Wallace Huo | Zhu Qizhen | 50 |