| Based on the real life and achievements of Dr. Kathy Magliato, this unique character-driven medical drama follows Dr. Alex Panttiere, an outspoken world-renowned heart-transplant surgeon and one of the few women in her field. Stubborn and fearless, Alex always operates on her own terms. Watch as she revels in a racy personal life, manages the daily demands of skeptical faculty and dutiful interns, and pushes the boundaries of medical science to impressive new heights. |
| Name | Character | Episodes |
|---|---|---|
| Melissa George | Dr. Alex Panttiere | 10 |
| Dave Annable | Dr. Pierce Harrison | 10 |
| Shelley Conn | Dr. Millicent Patel | 10 |
| Jamie Kennedy | Dr. Callahan | 10 |
| Joshua Leonard | Max | 10 |
| D.L. Hughley | Dr. Hackett | 10 |
| Don Hany | Dr. Jessie Shane | 10 |
| Maya Erskine | Nurse Ji-Sung | 10 |
| Rudy Martinez | Marty | 10 |
| Steele Stebbins | Carson | 6 |
| Michael Nouri | Gérard Panttiere | 1 |
| Brenda Bakke | Marie Panttiere | 1 |
| JoBeth Williams | Isobel Dixon | 1 |
| Hayley Sales | Deana Monroe | 1 |
| Luke Roessler | Little Boy | 1 |
| Andy Walken | Colin Tollefson | 1 |