| Ensign O'Toole is a military comedy that aired on NBC from September 23, 1962, to May 5, 1963, with 31-year-old Dean Jones in the title role of a nonchalant United States Navy ensign during the early 1960s. Jones, born in 1931 in Alabama and a Navy veteran of the Korean War, played an officer aboard the fictional U.S. Navy destroyer USS Appleby, which roamed the Pacific Ocean. |
| Name | Character | Episodes |
|---|---|---|
| Dean Jones | Ensign O'Toole | 32 |
| Jay C. Flippen | Chief Petty Officer Homer Nelson | 32 |
| Harvey Lembeck | Seaman Gabby Di Julio | 32 |
| Jack Albertson | Lieutenant Commander Virgil Stoner | 32 |
| Jack Mullaney | Lieutenant Rex St. John | 32 |
| Robert Sorrells | White | 13 |
| Beau Bridges | Spicer | 6 |
| Ken Berry | Lt. Melton | 5 |
| Beau Bridges | Seaman Howard Spicer | 2 |
| Robert Sorrells | Seaman Claude White | 2 |
| Gary Crosby | Ensign Baxter | 2 |
| James Hong | Headwaiter | 1 |
| Eddie Ryder | Al Shrieber | 1 |
| Steve Franken | Ensign Clifford Bender | 1 |
| Shary Marshall | Nurse | 1 |
| Jamie Farr | Penski | 1 |
| Stuart Margolin | Lt. Miller | 1 |
| Nita Talbot | Anna | 1 |
| Mike Farrell | Ferguson | 1 |
| Howard Morris | Delacroix | 1 |
| Dub Taylor | Clerk | 1 |
| Jack Carter | Steve Turner | 1 |
| Rosemary DeCamp | Leona | 1 |
| Bernard Fox | Hastings | 1 |
| Joe Higgins | Louie | 1 |
| Joe Higgins | Chief Henly | 1 |
| Harry Morgan | Charlie | 1 |
| William Schallert | Douglas Harper | 1 |
| Philip Ahn | Low Kong | 1 |
| Mako | Yamada, Jr. | 1 |
| Skip Ward | Lt. Ferguson | 1 |
| Ken Berry | Calucci | 1 |
| Ken Berry | Melton | 1 |
| Don Beddoe | Admiral Hornsby | 1 |
| Stubby Kaye | Tubby Mason | 1 |
| Émile Genest | Monti | 1 |
| Alan Caillou | Monte Cartwright | 1 |
| Peter Leeds | Charlie Kahn | 1 |
| Stafford Repp | Commodore | 1 |
| John McGiver | Arthur Ainsley | 1 |
| Charles Watts | Leslie | 1 |
| Jackie Joseph | Mary Lou | 1 |
| Herbie Faye | Smitty | 1 |
| Robert Kino | Mr. Yamada | 1 |
| Murray Alper | Chief Wales | 1 |
| Penny Santon | Mama Di Julio | 1 |
| Robert Emhardt | Rodney Frazer | 1 |
| Irene Tedrow | Mrs. Barnes | 1 |
| Romo Vincent | Papa Di Julio | 1 |
| Doris Packer | Mrs. Atherton | 1 |
| George Petrie | Lt. Commander Dickery | 1 |
| Davis Roberts | Swain | 1 |
| Sharon Hugueny | Juliet | 1 |
| Michael Ross | Gurney | 1 |
| Cal Bolder | Nathan | 1 |
| Alan Reed Jr. | Malloy | 1 |
| Dick Whittinghill | Announcer | 1 |
| Ransom M. Sherman | Congressman Torpin | 1 |
| Ransom M. Sherman | Stanley Cobb | 1 |
| Nancy Rennick | Patricia | 1 |
| Chana Eden | Illona | 1 |