| Name | Character | Episodes |
|---|---|---|
| Megan Fox | Banes / Herself - Megan Fox (archive footage) | 1 |
| Emma Roberts | Lena Haloway | 1 |
| Mila Kunis | Meg Griffin (archive footage) | 1 |
| Ciarán Hinds | 1 | |
| Eliza Dushku | 1 | |
| Jason Biggs | 1 | |
| Alex Borstein | Lois Griffin (archive footage) | 1 |
| Seth MacFarlane | Peter Griffin / Brian Griffin / Quagmire (archive footage) | 1 |
| William Sadler | John (archive footage) | 1 |
| Lacey Chabert | 1 | |
| Sela Ward | 1 | |
| John Viener | 1 | |
| Gregg Sulkin | Julian Fineman | 1 |
| Ian McNeice | 1 | |
| Michael Michele | Elyse Hargrove | 1 |
| Heather Locklear | 1 | |
| Janet Montgomery | 1 | |
| Patrick Warburton | Joe Swanson (archive footage) | 1 |
| Kellie Martin | Herself | 1 |
| Ian Anthony Dale | Liam | 1 |
| Kirk Cameron | 1 | |
| Erin Cahill | Rachel Haloway | 1 |
| Billy Campbell | Thomas Fineman | 1 |
| David Jensen | 1 | |
| Shiri Appleby | Herself | 1 |
| Melinda McGraw | Lydia | 1 |
| Brenda Koo | Ren | 1 |
| Chris Owen | Fiance | 1 |
| Shannen Doherty | 1 | |
| Mike Henry | Cleveland Brown (voice) | 1 |
| Corey Reynolds | Tack | 1 |
| Jeanine Mason | Hana Tate | 1 |
| Santiago Segura | Billy | 1 |
| Linc Hand | Officer | 1 |
| Daren Kagasoff | Alex Sheathes | 1 |
| Glenn Keogh | 1 | |
| Melinda Y. Cohen | Lena's Mother | 1 |