| Dr. Bashir Hamed, a Syrian doctor with battle-tested skills in emergency medicine, makes the difficult decision to flee his country and build a new life in Canada with his younger sister Amira. Bash works to navigate a new environment after earning a coveted residency in the Emergency Department of one of the best hospitals in Toronto, York Memorial. |
| Name | Character | Episodes |
|---|---|---|
| Hamza Haq | Dr. Bashir Hamed | 49 |
| Laurence Leboeuf | Dr. Magalie Leblanc | 49 |
| Ayisha Issa | Dr. June Curtis | 49 |
| Jim Watson | Dr. Theo Hunter | 49 |
| Torri Higginson | Claire Malone | 48 |
| Kenny Wong | Arnold De Luca | 47 |
| Sirena Gulamgaus | Amira Hamed | 35 |
| Sugith Varughese | Dr. Aajay Singh | 29 |
| John Hannah | Dr. Jed Bishop | 26 |
| Linda E. Smith | Dr. Wendy Atwater | 25 |
| Gord Rand | Mark Novak | 23 |
| Rekha Sharma | Neeta Devi | 21 |
| Katharine King So | Joanie Kwan | 15 |
| Eddie Guillaume | Lou | 15 |
| Marianne Farley | Elizabeth Bergeron | 13 |
| Linda E. Smith | Wendy Atwater | 9 |
| Nora Guerch | Raniya Kouri | 9 |
| Grace Lynn Kung | Vivian Barnes | 8 |
| Rick Roberts | Neil Olsen | 8 |
| Mark Rendall | Elliot | 6 |
| Macha Grenon | Muriel | 6 |
| Ellen David | Evelyn Roche | 6 |
| Charlotte Legault | Melissa Hunter | 6 |
| Atticus Mitchell | Jake Cooper | 5 |
| Gina James | Shay | 4 |
| Sean Baek | Dr. Andrew Zhang | 4 |
| Amanda Ip | Carmen | 4 |
| Alex Bisping | Pavel | 3 |
| Paul Zinno | Aiden Miller | 3 |
| Peter MacNeill | Mac Hinkley | 3 |
| Michael Riley | William Hunter | 3 |
| Eugene Clark | Marcus Curtis | 3 |
| Dov Tiefenbach | Percy Campbell | 3 |
| Jean Yoon | Lucy Sun-Yu | 3 |
| Carlo Mestroni | Tom Duncan | 3 |
| Charlotte Legault | Melissa Douglas-Hunter | 3 |
| Pascale Bussières | Denise Garneau | 3 |
| Stéphane Demers | Sylvain Leblanc | 3 |
| John Hannah | Jed Bishop | 2 |
| Catherine Bérubé | Jessica Brown | 2 |
| Joe Pingue | Andy | 2 |
| Geordie Johnson | Ren Campbell | 2 |
| Krista Bridges | Shelley | 2 |
| Derek McGrath | Donald | 2 |
| Marcel Jeannin | Jack Kline | 2 |
| Ron Lea | William Maxwell | 2 |
| Tattiawna Jones | Julia Baranski | 2 |
| Anne Bedian | Talia | 2 |
| David Eisner | Ray Grisholm | 2 |
| Julian DeZotti | Jason Jessup | 2 |
| Caitlyn Sponheimer | Dr. Erica Harris | 2 |
| Salvatore Antonio | Bruce Williams | 2 |
| Pierre Simpson | Gary Campbell | 2 |
| Rebecca Amzallag | Sonja Jessup | 2 |
| Letitia Brookes | Sandy | 2 |
| Katharine Isabelle | Marissa | 1 |
| Mayko Nguyen | Penny | 1 |
| Sophie Nélisse | Hannah Miller | 1 |
| Chris Sandiford | Nicholas | 1 |
| Kent McQuaid | Mr. Jackson | 1 |
| Andrew Moodie | 1 | |
| Conrad Pla | Frank Brezina | 1 |
| Saad Siddiqui | Captain David | 1 |
| Tommie-Amber Pirie | Della | 1 |
| Emily Piggford | Crystal | 1 |
| Teneisha Collins | Sheila | 1 |
| Rayisa Kondracki | Kyra | 1 |
| Ines Feghouli Bozon | TV Kid’s Show Voice (voice) | 1 |
| Elizabeth Saunders | Rita Carter | 1 |
| Percy Hynes White | Max | 1 |
| Lily Gao | Lucy Marsh | 1 |
| Martin Roach | 1 | |
| Anna Hopkins | Selena Ruiz | 1 |
| Nicky Guadagni | Lenore Callahan | 1 |
| Kimberly-Sue Murray | Zola | 1 |
| Andreas Apergis | Fireman (voice) | 1 |
| Sergio Di Zio | Fitz | 1 |
| Sydney Ozerov-Meyer | Alexia | 1 |
| Catherine Disher | Kathy | 1 |
| Mylène Dinh-Robic | Hannah's Mom | 1 |
| Mylène Dinh-Robic | Liz | 1 |
| Bruce Ramsay | Dr. Thibeault | 1 |
| Bruce Ramsay | Rusty Thibeault | 1 |
| Victor Andres Trelles Turgeon | Ephraim | 1 |
| Victoria Diamond | Emma De Marco | 1 |
| Arthur Holden | Announcement (voice) | 1 |
| Arthur Holden | Lock Down Announcer | 1 |
| Jayne Heitmeyer | Elena | 1 |
| Dillon Casey | Jack | 1 |
| Elana Dunkelman | Ms. Fair | 1 |
| Linda Kash | Kit Webber | 1 |
| Erin Agostino | Jenny | 1 |
| Vlasta Vrana | Walter Monroe | 1 |
| Cliff Saunders | Mr. Eldridge | 1 |
| Fulvio Cecere | Michael Bailey | 1 |
| Christian Jadah | Officer Parker | 1 |
| Rekha Sharma | Neeta Davi | 1 |
| David Reale | Evan | 1 |
| Dennis Andres | Ian | 1 |
| Barry Flatman | Patrick Camby | 1 |
| Gage Munroe | Cory | 1 |
| Joe Cobden | Alex | 1 |
| Paul Braunstein | John | 1 |
| Alex Mallari Jr. | Sully | 1 |
| Kyle Mac | Avrum | 1 |
| Neil Napier | Marty Roberts | 1 |
| Juliette Gosselin | Allie | 1 |
| Mary Walsh | Nancy Weiland | 1 |
| Marcel Jeannin | Murray Danbury | 1 |
| Katy Breier | Roberta | 1 |
| Bianca Gervais | Evelyn | 1 |
| Christopher Hayes | Neil | 1 |
| Ron Lea | Willam Maxwell | 1 |
| Sarah Booth | Leslie | 1 |
| Holly Uloth | Podcast Voice (voice) | 1 |
| Holly Uloth | Virtual Nurse | 1 |
| Natalie Lisinska | Alison | 1 |
| Kelly Craig | Truck Driver | 1 |
| Jason Cavalier | Angry Man | 1 |
| Dmitry Chepovetsky | Craig | 1 |
| Rick Roberts | Nick Olsen | 1 |
| Milton Barnes | Linus Johnson | 1 |
| Carly Street | Lily | 1 |
| Dan Petronijevic | Officer Brent | 1 |
| Dan Beirne | Ezra & Liam | 1 |
| Jeanie Calleja | Emily | 1 |
| Danny Blanco Hall | John Doe | 1 |
| Kwasi Songui | Power Line Worker | 1 |
| Claire Armstrong | Christie Todd | 1 |
| Bruce Dinsmore | Lawyer | 1 |
| Dan Lett | Chris Beaudry | 1 |
| Danielle Bourgon | Camille Beaudry | 1 |
| Edie Inksetter | Amber | 1 |
| Hanneke Talbot | Stacey | 1 |
| Kate McIninch | Dr. Parsons | 1 |
| John Ralston | Mr. Chandler | 1 |
| Jonathan Goad | Dwayne Clark | 1 |
| Alanna Bale | Laura Bailey | 1 |
| Wesley MacInnes | Ryan Ashcroft | 1 |
| Dale Whibley | Ethan | 1 |
| Thor Bishopric | Announcement (voice) | 1 |
| Thor Bishopric | Police Officer | 1 |
| Rodrigo Fernandez-Stoll | Javy Romero | 1 |
| Gavin Fox | Brock Paulson | 1 |
| Ted Dykstra | Eric | 1 |
| Jennifer Seguin | News Reporter | 1 |
| Jennifer Seguin | Robocall (voice) | 1 |
| Jennifer Seguin | Therapy Counselor | 1 |
| Jennifer Seguin | Drill Announcer | 1 |
| Sean Tucker | Anton | 1 |
| Jonas Chernick | Reese | 1 |
| Patricia Summersett | Sandra Parker | 1 |
| Sam Ashe Arnold | Dmitri | 1 |
| Deborah Drakeford | Paula Pederson | 1 |
| Emma Ferreira | Alyssa | 1 |
| Maria Herrera | Joan Serreno | 1 |
| Maria Herrera | Joan Sereno | 1 |
| Maria Herrera | Joan Serano | 1 |
| Kjartan Hewitt | 1 | |
| Thamela Mpumlwana | Trey | 1 |
| Alain Goulem | Bus Driver | 1 |
| Alain Goulem | George Watson | 1 |
| Oluniké Adeliyi | Makayla | 1 |
| Maia Jae Bastidas | Josie | 1 |
| Caitlyn Sponheimer | Erica Harris | 1 |
| Tina Jung | Sepi | 1 |
| Fiona Highet | 1 | |
| Paula Rivera | Maria Romero | 1 |
| Jake Lewis | Solomon Morris | 1 |
| Stefan Pleszczynski | Janitor | 1 |
| Patrick Kerton | Smasher at Wreck Bar | 1 |
| Rebecca Croll | Gale | 1 |
| Stephen Joffe | DJ | 1 |
| Andi Hubick | Esther Danbury | 1 |
| Arlen Aguayo-Stewart | Greta | 1 |
| Matthew MacFadzean | Officer D. Reid | 1 |
| Angela Galuppo | Amanda Gomes | 1 |
| Mark Antony Krupa | Worried Father | 1 |
| Anana Rydvald | Greta Harris | 1 |
| Tony Nash | Mahmoud | 1 |
| Murry Peeters | 1 | |
| Karl Graboshas | Reid | 1 |
| Jane Gilchrist | Mia Willis | 1 |
| Tom Rooney | Terrance Mann | 1 |
| Eileen Li | Harmony Mills | 1 |
| Meher Pavri | Dahab | 1 |
| Vivien Endicott Douglas | Lola | 1 |
| Olivia Scriven | Haley | 1 |
| Alika Autran | Lori | 1 |
| Linda Goranson | Lena Joseph | 1 |
| Eve Edwards | Trish Albrecht | 1 |
| Ron Kennell | Gideon | 1 |
| Mikaël Conde | Gavin Nair | 1 |
| Annie Briggs | Nicole Spencer | 1 |
| Lydia Zadel | Elena | 1 |
| Jonathan Kim | Vincent Chang | 1 |
| Jean Nicolai | 1 | |
| Sabrina Campilii | Cassie | 1 |
| Ali Kazmi | Gurjeet Sran | 1 |
| Vas Saranga | Navin Kutty | 1 |
| Steffi DiDomenicantonio | Cora Maxwell | 1 |
| Ashley Comeau | Lisa Williams | 1 |
| Tanisha Thammavongsa | Naomi Kaplan | 1 |
| Liz MacRae | Surgeon | 1 |
| Patrick Abellard | Cody | 1 |
| Tyrone Benskin | Eddie Jennings | 1 |
| Lenni-Kim | Lucas | 1 |
| Naomi Gaskin | Tracey Evans | 1 |
| Jameson Kraemer | Jamie | 1 |
| Alexandra Petrachuk | Susan | 1 |
| Madison Baines | Ruby Evans | 1 |
| Brandon McGibbon | Barry Carter | 1 |
| Miranda Calderon | Daphne Sampson | 1 |
| Duy Nguyen | Passerby | 1 |
| Dawn Lambing | Samantha Levesque | 1 |
| Robert Naylor | Dylan Carter | 1 |
| Jacob Neayem | Bertrand Braunstein | 1 |
| Rodrigues Williams | Randall Emett | 1 |
| Tonjha Richardson | Violet | 1 |
| Gugun Deep Singh | Sameer Gupta | 1 |
| Brian Sills | Harper | 1 |
| Daniel Gravelle | Danny | 1 |
| Dwight Ireland | Adrian | 1 |
| Bonnie Mak | Judge | 1 |
| Nir Guzinski | Dr. Svensson | 1 |
| Daniel Maslany | Kyle | 1 |
| Jason Blicker | Leon | 1 |
| Alain Dahan | Surgeon | 1 |
| Jesse Camacho | Eugene | 1 |
| Shoshana Wilder | Deena | 1 |
| Dave Campbell | Sworn-In Citizen #1 | 1 |
| Russell Yuen | Dr. Alan Yong | 1 |
| Fred Nguyen Khan | Mr. Conor | 1 |
| Morgan Kohan | Kelsey Grisholm | 1 |
| Josh Cruddas | 1 | |
| Susanna Fournier | Van | 1 |